This site is targeted at medical and radiology professionals, contains user contributed content, and material that may be confusing to a lay audience. Use of this site implies acceptance of our Terms of Use.

Rhabdomyosarcoma staging

Dr Jeremy Jones and Dr Frank Gaillard et al.

Staging of rhabdomyosarcoma is based on the Lawrence/Gehan Staging System which comprises of a combination of pretreatment staging and postoperative clinical grouping.

Stage

stage I : orbit, eyelid, head and neck (excluding parameningeal), genitourinary (non-bladder, non-prostate), N0 or 1, M0
stage II : bladder, prostate, extremity, trunk, parameningeal, other, < 5 cm, N0, M0
stage III : Bladder, prostate, extremity, trunk, parameningeal, other, > 5 cm, N0 or 1, M0
stage IV : all others, any N, M1

IRS group postsurgical pathologic grouping

group I
- Ia : confined to organ of origin or muscle, completely resected (clear margins, negative regional nodes)
- Ib : local extension beyond to organ or muscle of origin, completely resected (clear margins, negative regional nodes)
group II
- IIa : microscopic disease remaining at margins : negative regional nodes
- IIb : positive regional nodes : negative margins
- IIc : microscopic disease remaining at margins and positive regional nodes
group III : incomplete resection or biopsy findings indicating gross residual disease
group IV : distant metastases