Rosenthal fibers

Last revised by Henry Knipe on 14 May 2018

Rosenthal fibers are astrocytic cytoplasmic inclusions, typically found in areas of longstanding gliosis. These elongated or "corkscrew" structures occur within astrocytic processes and are brightly eosinophilic (stain bright pink on the H&E stain) 1-3. They represent astrocytic processes swollen with glial filaments and amorphous granular material 3

They can be seen in a number conditions, all of which have prominent fibrillary gliosis. Such conditions include 1,3

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.