This article specifically relates to spinal arachnoid cysts. For a general discussion of arachnoid cysts refer to the main article: arachnoid cyst.
Spinal arachnoid cysts may present at any age. There is no gender predilection.
Most spinal arachnoid cysts are asymptomatic and are discovered incidentally. If present, clinical symptoms may include pain, weakness, numbness or bladder/bowel incontinence. Symptoms may be exacerbated with postural changes and the Valsalva maneuver.
As with any arachnoid cyst, spinal arachnoid cysts are CSF filled sacs contained by arachnoid mater. The degree of communication with the surrounding CSF space is variable with some cyst freely communicating and other not at all 9.
They may be congenital or acquired. Secondary arachnoid cysts are usually due to trauma, haemorrhage, inflammation, surgery or lumbar puncture 3,4.
Most primary intradural spinal arachnoid cysts are dorsal to the cord. They occur at the following locations:
- thoracic: 80%
- cervical: 15%
- lumbar: 5%
Secondary spinal arachnoid cysts can be located anywhere.
A compressed cord that is displaced anteriorly 3. Most arachnoid cyst eventually opacify with contrast, although the rate at which they do so is variable 7,9. In many instances the cyst opacifies readily and as such it can be challenging to diagnose with certainty. Early scanning, accepting the need to possible more delayed scanning if appropriate CSF mixing is not achieved is advisable, in an effort to 'catch' the cyst before it is iso-dense to CSF. This may necessitate introduction of contrast on the CT table rather than in fluoroscopy.
As the cysts follow the intensity of CSF and their walls are generally not visible, they may not be identified unless the cord is displaced.
- T1: CSF intensity
- T2: CSF intensity, may even be brighter than CSF on account of no signal loss from pulsation/flow 8
- T1 C+ (Gd): no contrast enhancement
- phase-contrast imaging: decreased CSF flow within the cyst 7
- DWI: No evidence of restricted diffusion
Treatment and prognosis
Incidental asymptomatic cysts are managed conservatively. Symptomatic cysts can be treated with surgical excision. An important component of surgical treatment of epidural cysts includes closure of the arachnoid defect that can be a source of a CSF leak.
For intradural arachnoid cysts a number of alternative diagnoses should be considered:
herniated ventral cord
- focal cord deformity
- phase-contrast MRI: absence of CSF flow ventral to the herniated cord and a normal CSF flow pattern dorsal to the cord 7
- can be challenging to distinguish, and myelography may be helpful
spinal epidermoid cyst
- bright on DWI (as in the brain, spinal epidermoids are differentiated from arachnoid cysts by their brightness on DWI)
spinal dermoid cyst
- most common location is lumbar spine
- imaging characteristics are variable but usually resemble fat 3
- spinal hydatid cyst
- most commonly extradural (intradural extramedullary lesions are extremely rare)
- usually multiloculated
- may show minimal enhancement
- spinal cysticercosis
- peripheral enhancement
- usually multiloculated
Rarely extradural cysts may be considered, although they are usually clearly not within the dura. They include:
- 1. Lolge S, Chawla A, Shah J et-al. MRI of spinal intradural arachnoid cyst formation following tuberculous meningitis. Br J Radiol. 2004;77 (920): 681-4. doi:10.1259/bjr/90641678 - Pubmed citation
- 2. Hamamcioglu MK, Kilincer C, Hicdonmez T et-al. Giant cervicothoracic extradural arachnoid cyst: case report. Eur Spine J. 2006;15 Suppl 5 : 595-8. doi:10.1007/s00586-005-0041-4 - Free text at pubmed - Pubmed citation
- 3. Osborn AG. Diagnostic neuroradiology. Mosby Inc. (1994) ISBN:0801674867. Read it at Google Books - Find it at Amazon
- 4. Brant WE, Helms CA. Fundamentals of Diagnostic Radiology. Lippincott Williams & Wilkins. (2007) ISBN:0781761352. Read it at Google Books - Find it at Amazon
- 5. Grossman RI, Yousem DM. Neuroradiology, the requisites. Mosby Inc. (2003) ISBN:032300508X. Read it at Google Books - Find it at Amazon
- 6. Wenger M, Zobor N, Markwalder R et-al. Intradural extramedullary arachnoid cyst of the thoracic spine associated with cord compression. J Clin Neurosci. 2007;14 (7): 693-6. doi:10.1016/j.jocn.2006.02.011 - Pubmed citation
- 7. Brugières P, Malapert D, Adle-biassette H et-al. Idiopathic spinal cord herniation: value of MR phase-contrast imaging. AJNR Am J Neuroradiol. 1999;20 (5): 935-9. AJNR Am J Neuroradiol (citation) - Pubmed citation
- 8. Khosla A, Wippold FJ. CT myelography and MR imaging of extramedullary cysts of the spinal canal in adult and pediatric patients. AJR Am J Roentgenol. 2002;178 (1): 201-7. AJR Am J Roentgenol (citation) - Pubmed citation
- 9. Silbergleit R, Brunberg JA, Patel SC et-al. Imaging of spinal intradural arachnoid cysts: MRI, myelography and CT. Neuroradiology. 1998;40 (10): 664-8. Neuroradiology (link) - Pubmed citation
Synonyms & Alternative Spellings
|Synonyms or Alternative Spelling||Include in Listings?|
|Arachnoid cysts of spine||✗|
|Arachnoid cyst of spine||✗|
|Spinal arachnoid cysts||✗|
|Arachnoid cyst of the spine||✗|
|Arachnoid cyst involving the spine||✗|