Spondylolysis

Changed by Weiling Tan, 28 Jan 2023
Disclosures - updated 4 Nov 2022: Nothing to disclose

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Spondylolysis is a defect in the pars interarticularis of the neural arch, the portion of the neural arch that connects the superior and inferior articular facets. It is commonly known as pars interarticularis defect or more simply as pars defect

Epidemiology

Spondylolysis is present in ~5% of the population 2 and higher in the adolescent athletic population. It is more common in men than in women 1.

Associations

Clinical presentation

Spondylolysis is commonly asymptomatic. Symptomatic patients often have pain with extension and/or rotation of the lumbar spine. Approximately 25% of individuals with spondylolysis have symptoms at some time.

It is a common cause of low back pain in adolescents and may be the cause of low back pain in ~50% of adolescent athletes 7.

Pathology

Spondylolysis may be developmental or acquired. Developmental defects may develop in patients <10 years 7. Acquired defects have two main mechanisms:

  • repeated microtrauma, resulting in a stress injury and eventual fracture of the pars interarticularis; a dysplastic pars is usually present

  • traumatic pars defects result from high-energy trauma where there is hyperextension of the lumbar spine and are rare in a congenitally normal vertebra

Location
  • ~90% of cases of spondylolysis occur at the L5 level and ~10% occur at the L4 level 1,2

  • unilateral or bilateral

Radiographic features

Imaging features depend on the age of the lesion. CT is considered the gold standard although MRI should be used as the first-line imaging modality in adolescents 7.

Plain radiograph
  • limited sensitivity compared to SPECT and CT 4

  • Scotty dog sign: on oblique radiographs, a break in the pars interarticularis can have the appearance of a collar around the dog's neck

  • inverted Napoleon hat sign

CT/MRI
  • wide-canal sign may be present on sagittal images when there is spondylolisthesis 3

  • deviation of the spinous process

  • sclerosis of the contralateral pedicle

Hollenberg classification

This is a classification system mostly based on MRI features but correlates well with SPECT-CT 6,7:

  • grade 0: normal pars interarticularis; MRI: no signal abnormality, pars interarticularis intact

  • grade I: stress reaction; MRI: marrow oedema; intact cortical margins

  • grade II: incomplete stress fracture; MRI: marrow oedema; incomplete cortical fracture or fissure

  • grade III: acute complete stress fracture; MRI: marrow oedema; complete cortical fracture extending through pars interarticularis

  • grade IV: chronic stress fracture; MRI: no marrow oedema; fractures completely extending through pars interarticularis

Treatment and prognosis

Surgery is only considered in rare circumstances as most cases respond to conservative management 2. Incomplete fractures demonstrate good healing rates with conservative management 7.

Differential diagnosis

  • -<p><strong>Spondylolysis</strong> is a defect in the <a href="/articles/pars-interarticularis">pars interarticularis</a> of the neural arch, the portion of the neural arch that connects the superior and inferior articular facets. It is commonly known as<strong> pars interarticularis defect</strong> or more simply as <strong>pars defect</strong>. </p><h4>Epidemiology</h4><p>Spondylolysis is present in ~5% of the population <sup>2</sup> and higher in the adolescent athletic population. It is more common in men than in women<sup> 1</sup>.</p><h5>Associations</h5><ul>
  • -<li><p>~65% of patients with spondylolysis will progress to <a href="/articles/spondylolisthesis-1">spondylolisthesis</a> <sup>2</sup>, which is seen radiographically in ~25% <sup>4</sup>; in most patients this occurs before the age of 16</p></li>
  • -<li><p><a href="/articles/spina-bifida-occulta">spina bifida occulta</a></p></li>
  • -<li><p>idiopathic <a href="/articles/scoliosis">scoliosis</a>: ~5% <sup>8</sup></p></li>
  • -</ul><h4>Clinical presentation</h4><p>Spondylolysis is commonly asymptomatic. Symptomatic patients often have pain with extension and/or rotation of the lumbar spine. Approximately 25% of individuals with spondylolysis have symptoms at some time.</p><p>It is a common cause of <a href="/articles/low-back-pain">low back pain</a> in adolescents and may be the cause of low back pain in ~50% of adolescent athletes <sup>7</sup>.</p><h4>Pathology</h4><p>Spondylolysis may be developmental or acquired. Developmental defects may develop in patients &lt;10 years <sup>7</sup>. Acquired defects have two main mechanisms:</p><ul>
  • -<li><p>repeated microtrauma, resulting in a <a href="/articles/stress-fracture-2">stress injury</a> and eventual fracture of the pars interarticularis; a dysplastic pars is usually present</p></li>
  • -<li><p>traumatic pars defects result from high-energy trauma where there is hyperextension of the lumbar spine and are rare in a congenitally normal vertebra</p></li>
  • -</ul><h5>Location</h5><ul>
  • -<li><p>~90% of cases of spondylolysis occur at the L5 level and ~10% occur at the L4 level <sup>1,2</sup></p></li>
  • -<li><p>unilateral or bilateral</p></li>
  • -</ul><h4>Radiographic features</h4><p>Imaging features depend on the age of the lesion. CT is considered the gold standard although MRI should be used as the first-line imaging modality in adolescents <sup>7</sup>.</p><h5>Plain radiograph</h5><ul>
  • -<li><p>limited sensitivity compared to SPECT and CT <sup>4</sup></p></li>
  • -<li><p><a href="/articles/scottie-dog-sign-spine">Scotty dog sign</a>: on oblique radiographs, a break in the pars interarticularis can have the appearance of a collar around the dog's neck</p></li>
  • -<li><p><a href="/articles/inverted-napoleon-hat-sign">inverted Napoleon hat sign</a></p></li>
  • -</ul><h5>CT/MRI</h5><ul>
  • -<li><p><a href="/articles/wide-canal-sign">wide-canal sign</a> may be present on sagittal images when there is spondylolisthesis <sup>3</sup></p></li>
  • -<li><p>deviation of the spinous process</p></li>
  • -<li><p>sclerosis of the contralateral pedicle</p></li>
  • -</ul><h5>Hollenberg classification</h5><p>This is a classification system mostly based on MRI features but correlates well with SPECT-CT <sup>6,7</sup>:</p><ul>
  • -<li><p><strong>grade 0:</strong> normal pars interarticularis; MRI: no signal abnormality, pars interarticularis intact</p></li>
  • -<li><p><strong>grade I:</strong> stress reaction; MRI: marrow oedema; intact cortical margins</p></li>
  • -<li><p><strong>grade II:</strong> incomplete stress fracture; MRI: marrow oedema; incomplete cortical fracture or fissure</p></li>
  • -<li><p><strong>grade III: </strong>acute complete stress fracture; MRI: marrow oedema; complete cortical fracture extending through pars interarticularis</p></li>
  • -<li><p><strong>grade IV: </strong>chronic stress fracture; MRI: no marrow oedema; fractures completely extending through pars interarticularis</p></li>
  • -</ul><h4>Treatment and prognosis</h4><p>Surgery is only considered in rare circumstances as most cases respond to conservative management <sup>2</sup>. Incomplete fractures demonstrate good healing rates with conservative management <sup>7</sup>.</p><h4>Differential diagnosis</h4><ul>
  • -<li><p><a href="/articles/osteoid-osteoma">osteoid osteoma</a></p></li>
  • -<li><p><a href="/articles/osteomyelitis">osteomyelitis</a></p></li>
  • -<li><p><a href="/articles/retroisthmic-cleft" title="Retroisthmic cleft">retroisthmic cleft</a></p></li>
  • +<p><strong>Spondylolysis</strong> is a defect in the <a href="/articles/pars-interarticularis">pars interarticularis</a> of the neural arch, the portion of the neural arch that connects the superior and inferior articular facets. It is commonly known as<strong> pars interarticularis defect</strong> or more simply as <strong>pars defect</strong>. </p><h4>Epidemiology</h4><p>Spondylolysis is present in ~5% of the population <sup>2</sup> and higher in the adolescent athletic population. It is more common in men than in women<sup> 1</sup>.</p><h5>Associations</h5><ul>
  • +<li><p>~65% of patients with spondylolysis will progress to <a href="/articles/spondylolisthesis-1">spondylolisthesis</a> <sup>2</sup>, which is seen radiographically in ~25% <sup>4</sup>; in most patients this occurs before the age of 16</p></li>
  • +<li><p><a href="/articles/spina-bifida-occulta">spina bifida occulta</a></p></li>
  • +<li><p>idiopathic <a href="/articles/scoliosis">scoliosis</a>: ~5% <sup>8</sup></p></li>
  • +</ul><h4>Clinical presentation</h4><p>Spondylolysis is commonly asymptomatic. Symptomatic patients often have pain with extension and/or rotation of the lumbar spine. Approximately 25% of individuals with spondylolysis have symptoms at some time.</p><p>It is a common cause of <a href="/articles/low-back-pain">low back pain</a> in adolescents and may be the cause of low back pain in ~50% of adolescent athletes <sup>7</sup>.</p><h4>Pathology</h4><p>Spondylolysis may be developmental or acquired. Developmental defects may develop in patients &lt;10 years <sup>7</sup>. Acquired defects have two main mechanisms:</p><ul>
  • +<li><p>repeated microtrauma, resulting in a <a href="/articles/stress-fracture-2">stress injury</a> and eventual fracture of the pars interarticularis; a dysplastic pars is usually present</p></li>
  • +<li><p>traumatic pars defects result from high-energy trauma where there is hyperextension of the lumbar spine and are rare in a congenitally normal vertebra</p></li>
  • +</ul><h5>Location</h5><ul>
  • +<li><p>~90% of cases of spondylolysis occur at the L5 level and ~10% occur at the L4 level <sup>1,2</sup></p></li>
  • +<li><p>unilateral or bilateral</p></li>
  • +</ul><h4>Radiographic features</h4><p>Imaging features depend on the age of the lesion. CT is considered the gold standard although MRI should be used as the first-line imaging modality in adolescents <sup>7</sup>.</p><h5>Plain radiograph</h5><ul>
  • +<li><p>limited sensitivity compared to SPECT and CT <sup>4</sup></p></li>
  • +<li><p><a href="/articles/scottie-dog-sign-spine">Scotty dog sign</a>: on oblique radiographs, a break in the pars interarticularis can have the appearance of a collar around the dog's neck</p></li>
  • +<li><p><a href="/articles/inverted-napoleon-hat-sign">inverted Napoleon hat sign</a></p></li>
  • +</ul><h5>CT/MRI</h5><ul>
  • +<li><p><a href="/articles/wide-canal-sign">wide-canal sign</a> may be present on sagittal images when there is spondylolisthesis <sup>3</sup></p></li>
  • +<li><p>deviation of the spinous process</p></li>
  • +<li><p>sclerosis of the contralateral pedicle</p></li>
  • +</ul><h5>Hollenberg classification</h5><p>This is a classification system mostly based on MRI features but correlates well with SPECT-CT <sup>6,7</sup>:</p><ul>
  • +<li><p><strong>grade 0:</strong> normal pars interarticularis; MRI: no signal abnormality, pars interarticularis intact</p></li>
  • +<li><p><strong>grade I:</strong> stress reaction; MRI: marrow oedema; intact cortical margins</p></li>
  • +<li><p><strong>grade II:</strong> incomplete stress fracture; MRI: marrow oedema; incomplete cortical fracture or fissure</p></li>
  • +<li><p><strong>grade III: </strong>acute complete stress fracture; MRI: marrow oedema; complete cortical fracture extending through pars interarticularis</p></li>
  • +<li><p><strong>grade IV: </strong>chronic stress fracture; MRI: no marrow oedema; fractures completely extending through pars interarticularis</p></li>
  • +</ul><h4>Treatment and prognosis</h4><p>Surgery is only considered in rare circumstances as most cases respond to conservative management <sup>2</sup>. Incomplete fractures demonstrate good healing rates with conservative management <sup>7</sup>.</p><h4>Differential diagnosis</h4><ul>
  • +<li><p><a href="/articles/osteoid-osteoma">osteoid osteoma</a></p></li>
  • +<li><p><a href="/articles/osteomyelitis">osteomyelitis</a></p></li>
  • +<li><p><a href="/articles/retroisthmic-cleft" title="Retroisthmic cleft">retroisthmic cleft</a></p></li>
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 Case 2Case 1: bilateral L5 pars fracture
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Case 42: bilateral L5 pars defect
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Case 76: on MRIbilateral L5 pars defect
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Case 109: L5 pars defect
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Image 10 X-ray (Oblique- zoomed) ( create )

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