Tectal plate gliomas are encountered in children and adolescents 4. A male predilection has sometimes been reported although this is by no means certain 3.
An association with neurofibromatosis type I (NF1) has been reported 3-4.
The vast majority of lesions are low grade astrocytoma, although occasionally other glial series tumours are encountered in the tectal region including ependymoma, ganglioglioma and primitive neuroectodermal tumours (PNET) 3.
Typical CT finding is homogeneous expansion of tectal plate, isodense to grey matter with minimal enhancement on postcontrast images 1,3. On CT it is not uncommon to find a central tectal calcification 2-3.
Typically the tumours demonstrate expansion of the tectal plate by a solid nodule of tissue.
- T1: iso to slightly hypointense to grey matter 1-3
- T2: hyperintense to grey matter
- T1 C+ (Gd): usually no enhancement
With time the mass can develop small cystic spaces (sometimes associated with neurological deficits) or calcification 3.
Higher grade tumours tend to be larger and tend to enhance more vividly 3.
Treatment and prognosis
As tectal plate gliomas are low grade and often very slow growing, shunting is often the only required intervention for long term survival. As surgical biopsy can have significant morbidity in this area, usually the diagnosis is made on imaging findings alone.
In the minority of patients who progress, radiotherapy often leads to local control or even tumour regression 2. Surgical excision is sometimes necessary 3.
Imaging predictors of patients who will need further treatment include a size greater than 2.5 cm and presence of contrast enhancement 3.
When the tectum is near-normal then the differential is largely limited to:
- no mass lesion
- a focal stenosis or web may be visible
With larger lesions, where the mass is not definitely arising from the tectal plate then the differential is essentially that of a pineal region mass and therefore includes:
- pineal parenchymal tumours and germ cell tumours
- pineal cyst
- cerebral metastasis
- cavernous malformation
In patients with NF1 a hamartoma should also be considered. They tend to have some T1 hyperintensity 4.
- WHO classification of CNS tumours
- diffuse astrocytic tumours
- diffuse astrocytoma grading
- low grade astrocytoma
- anaplastic astrocytoma
- glioma treatment response assessment in clinical trials
- multicentric glioblastoma
- multifocal glioblastoma
- O6-Methylguanine-DNA methyltransferase (MGMT)
- isocitrate dehydrogenase 1 (IDH1)
- giant cell glioblastoma
- gliomatosis cerebri
- radiation-induced gliomas
- localised astrocytic tumours
- specific locations
- 1. Friedman DP. Extrapineal abnormalities of the tectal region: MR imaging findings. AJR Am J Roentgenol. 1992;159 (4): 859-66. AJR Am J Roentgenol (abstract) - Pubmed citation
- 2. Keating RF, Goodrich JT, Packer RJ. Tumors of the pediatric central nervous system. George Thieme Verlag. (2001) ISBN:0865778485. Read it at Google Books - Find it at Amazon
- 3. Poussaint TY, Kowal JR, Barnes PD et-al. Tectal tumors of childhood: clinical and imaging follow-up. AJNR Am J Neuroradiol. 1998;19 (5): 977-83. AJNR Am J Neuroradiol (abstract) - Pubmed citation
- 4. DinçEr A, Yener U, ÖZek MM. Hydrocephalus in patients with neurofibromatosis type 1: MR imaging findings and the outcome of endoscopic third ventriculostomy. AJNR Am J Neuroradiol. 2011;32 (4): 643-6. AJNR Am J Neuroradiol (full text) - doi:10.3174/ajnr.A2357 - Pubmed citation
- 5. Arora AM, Puri SKM, Upreti LM. Brain Imaging: Case Review Series. Jaypee Brothers Medical Pub. (2011) ISBN:9350253895. Read it at Google Books - Find it at Amazon
Synonyms & Alternative Spellings
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|Tectal plate gliomas||✗|