Thyroid acropachy

Changed by Jeremy Jones, 18 Feb 2018

Updates to Article Attributes

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Thyroid acropachy is an unusual presentation of autoimmune thyroid disease, (~1% of patients with Graves disease). It can occur in hyperthyroid, euthyroid, hypothyroid, or even post-treatment patients. It is almost always associated with thyroid ophthalmopathy

Epidemiology

The majority of patients are smokers.

Clinical presentation

Clinically, it presents with soft tissue swelling, finger clubbing and a periosteal reaction of the extremities.

Radiographic features

Plain radiograph
  • prominent smooth flowing periosteal reaction affecting the hands and feet. It is usually bilateral and symmetrical involving the tubular bones of hands and feet
  • may also be evidence of soft tissue swelling (especially lower limbs)

Differential diagnosis

  • -<p><strong>Thyroid acropachy</strong> is an unusual presentation of autoimmune thyroid disease, (~1% of patients with <a href="/articles/graves-disease">Graves disease</a>). It can occur in hyperthyroid, euthyroid, hypothyroid, or even post-treatment patients. It is almost always associated with <a href="/articles/thyroid-associated-orbitopathy">thyroid ophthalmopathy</a>. </p><h4>Epidemiology</h4><p>The majority of patients are smokers.</p><h4>Clinical presentation</h4><p>Clinically, it presents with soft tissue swelling, finger clubbing and a periosteal reaction of the extremities.</p><h4>Radiographic features</h4><h5>Plain radiograph</h5><ul>
  • +<p><strong>Thyroid acropachy</strong> is an unusual presentation of autoimmune thyroid disease, (~1% of patients with <a href="/articles/graves-disease">Graves disease</a>). It can occur in hyperthyroid, euthyroid, hypothyroid, or even post-treatment patients. It is almost always associated with <a href="/articles/thyroid-associated-orbitopathy-1">thyroid ophthalmopathy</a>. </p><h4>Epidemiology</h4><p>The majority of patients are smokers.</p><h4>Clinical presentation</h4><p>Clinically, it presents with soft tissue swelling, finger clubbing and a periosteal reaction of the extremities.</p><h4>Radiographic features</h4><h5>Plain radiograph</h5><ul>
  • -<li><a href="/articles/vitamin-a-related-abnormalities">hypervitaminosis A</a></li>
  • +<li><a href="/articles/vitamin-a-1">hypervitaminosis A</a></li>

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