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A tuberculoma or tuberculous granuloma is a well defined focal mass that results from infection with Mycobacterium tuberculosis, and is one of several morphological forms of tuberculous disease. Tuberculomas occur most commonly in the brain and lung.

Please refer to the article on CNS tuberculosis for a specific discussion of that entity. 


Macroscopically, a tuberculoma is a well defined firm nodule.  Histologically it consists of a central core of caseating necrosis with a surrounding wall of a granulomatous reaction containing Langhans giant cells, epithelioid histiocytes and lymphocytes.


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