Vertebral body squaring refers to loss of normal concavity of the anterior border. It is seen in a variety of conditions.
Ankylosing spondylitis is the most common cause of vertebral body squaring. It usually involves multiple levels and typically begins in the lumbar spine. Vertebral body squaring occurs after the shiny corner sign/Romanus lesion and precedes bamboo spine.
Paget disease of bone
Paget disease of bone can result in squaring of the vertebral bodies although it usually involves individual vertebrae and is associated with other signs typical of the condition, e.g. bony expansion, trabeculation and cortical thickening.
There are many inflammatory arthritides, but while vertebral body squaring can occur it is an uncommon manifestation of these conditions. Examples include:
Down syndrome may result in vertebral body squaring, but it is not a classical finding.
- seronegative spondyloarthritides
- Jaccoud arthropathy
- juvenile idiopathic arthritis
- lyme arthritis
- rheumatoid arthritis
- systemic lupus erythematosus
- erosive osteoarthritis
- osteoarthritis (mnemonic)
- primary cystic arthrosis of the hip
- rapidly destructive osteoarthritis of the hip
- secondary synovial osteochondromatosis
- miscellaneous disorders
- related articles
- 1. Eisenberg RL. Clinical Imaging, An Atlas of Differential Diagnosis. Lippincott Williams & Wilkins. (2009) ISBN:0781788609. Read it at Google Books - Find it at Amazon
- 2. Ward MM, Learch TJ, Weisman MH. Cervical vertebral squaring in patients without spondyloarthritis. J. Rheumatol. 2012;39 (9): 1900. doi:10.3899/jrheum.120322 - Free text at pubmed - Pubmed citation
- 3. Cho H, Kim T, Kim TH et-al. Spinal mobility, vertebral squaring, pulmonary function, pain, fatigue, and quality of life in patients with ankylosing spondylitis. Ann Rehabil Med. 2013;37 (5): 675-82. doi:10.5535/arm.2013.37.5.675 - Free text at pubmed - Pubmed citation