This site is targeted at medical and radiology professionals, contains user contributed content, and material that may be confusing to a lay audience. Use of this site implies acceptance of our Terms of Use.

Vertebral body squaring

Vertebral body squaring refers to loss of normal concavity of the anterior border. It is seen in a variety of conditions, e.g. ankylosing spondylitis, Paget disease of boneinflammatory arthritides and Down syndrome.

Example conditions

Ankylosing spondylitis

Ankylosing spondylitis is the most common cause of vertebral body squaring. It usually involves multiple levels and typically begins in the lumbar spine.  Vertebral body squaring occurs after the shiny corner sign / Romanus lesion and precedes bamboo spine.

Paget disease of bone

Paget disease of bone can result in squaring of the vertebral bodies although it usually involves individual vertebrae and is associated with other signs typical of the condition, e.g. bony expansion, trabeculation and cortical thickening.

Inflammatory arthritides

There are many inflammatory arthritides, but while vertebral body squaring can occur it is an uncommon manifestation of these conditions.  Examples include:

Down syndrome

Down syndrome may result in vertebral body squaring, but it is not a classical finding.

Updating… Please wait.
Loadinganimation

Alert_accept

Error Unable to process the form. Check for errors and try again.

Alert_accept Thank you for updating your details.