WHO classification of odontogenic and maxillofacial bone tumors

Changed by Yuranga Weerakkody, 4 Jul 2018

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The 2005 WHO histological classification of odontogenic tumours lays out a classification system for neoplasms and other tumours related to the odontogenic apparatus. At the time of writing (2016), it is still the most widely used classification system although a new revision is due to come up in 2017.

Classification

Malignant tumours

odontogenic carcinomas
- malignant ameloblastoma
- ameloblastic carcinoma: primary type
- ameloblastic carcinoma: secondary type (dedifferentiated), intraosseous
- ameloblastic carcinoma: secondary type (dedifferentiated), peripheral
- primary intraosseous squamous cell carcinoma: solid type
- primary intraosseous squamous cell carcinoma derived from keratocystic odontogenic tumour
- primary intraosseous squamous cell carcinoma derived from an odontogenic cyst
- clear cell odontogenic carcinoma
- ghost cell odontogenic carcinoma
odontogenic sarcomas
- ameloblastic fibrosarcoma (ameloblastic sarcoma)
- ameloblastic fibrodentinosarcoma and fibro-odontosarcoma

Benign

odontogenic epithelium mature, fibrous stroma without odontogenic ectomesenchyme
- ameloblastoma: solid/multicystic type
- ameloblastoma: extraosseous/peripheral type
- ameloblastoma: desmoplastic type
- ameloblastoma: unicystic type
- squamous odontogenic tumour
- calcifying epithelial odontogenic tumour (Pindborg tumour)
- adenomatoid odontogenic tumour
- keratocystic odontogenic tumour
odontogenic epithelium with odontogenic ectomesenchyme, with or without hard tissue formation
- ameloblastic fibroma
- ameloblastic fibrodentinoma (dentinoma)
- ameloblastic fibro-odontoma
- odontoma
  - odontoma: complex type
  - odontoma: compound type
- odontoameloblastoma
- calcifying cystic odontogenic cyst
- dentinogenic ghost cell tumour
mesenchyme and/or odontogenic ectomesenchyme with or without odontogenic epithelium
- odontogenic fibroma
- odontogenic myxoma / myxofibroma
- cementoblastoma

Bone-related lesions

Other tumours

melanotic neuroectodermal tumour of infancy

~~-<li>keratocystic odontogenic tumour</li>~~
+<li><a href="/articles/odontogenic-keratocyst">keratocystic odontogenic tumour</a></li>
~~-<a href="/articles/osseous-dysplasias">osseous dysplasias</a><ul><li><a href="/articles/cemento-osseous-dysplasia-1">cemento-osseous dysplasia</a></li></ul>~~
+<a href="/articles/osseous-dysplasias">osseous dysplasias</a><ul><li>
+<a href="/articles/cemento-osseous-dysplasia-1">cemento-osseous dysplasia</a><ul>
+<li><a href="/articles/periapical-cemental-dysplasia">periapical cemental dysplasia</a></li>
+<li><a href="/articles/focal-cemento-osseous-dysplasia">focal cemento-osseous dysplasia</a></li>
+<li><a href="/articles/florid-cemento-osseous-dysplasia">florid cemento-osseous dysplasia</a></li>
+</ul>
+</li></ul>

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