WHO classification of odontogenic and maxillofacial bone tumors
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The 2005 WHO histological classification of odontogenic tumours lays out a classification system for neoplasms and other tumours related to the odontogenic apparatus. At the time of writing (2016), it is still the most widely used classification system although a new revision is due to come up in 2017.
Classification
Malignant tumours
-
odontogenic carcinomas
- malignant ameloblastoma
- ameloblastic carcinoma: primary type
- ameloblastic carcinoma: secondary type (dedifferentiated), intraosseous
- ameloblastic carcinoma: secondary type (dedifferentiated), peripheral
- primary intraosseous squamous cell carcinoma: solid type
- primary intraosseous squamous cell carcinoma derived from keratocystic odontogenic tumour
- primary intraosseous squamous cell carcinoma derived from an odontogenic cyst
- clear cell odontogenic carcinoma
- ghost cell odontogenic carcinoma
-
odontogenic sarcomas
- ameloblastic fibrosarcoma (ameloblastic sarcoma)
- ameloblastic fibrodentinosarcoma and fibro-odontosarcoma
Benign
-
odontogenic epithelium mature, fibrous stroma without odontogenic ectomesenchyme
- ameloblastoma: solid/multicystic type
- ameloblastoma: extraosseous/peripheral type
- ameloblastoma: desmoplastic type
- ameloblastoma: unicystic type
- squamous odontogenic tumour
- calcifying epithelial odontogenic tumour (Pindborg tumour)
- adenomatoid odontogenic tumour
- keratocystic odontogenic tumour
-
odontogenic epithelium with odontogenic ectomesenchyme, with or without hard tissue formation
- ameloblastic fibroma
- ameloblastic fibrodentinoma (dentinoma)
- ameloblastic fibro-odontoma
-
odontoma
- odontoma: complex type
- odontoma: compound type
- odontoameloblastoma
- calcifying cystic odontogenic cyst
- dentinogenic ghost cell tumour
-
mesenchyme and/or odontogenic ectomesenchyme with or without odontogenic epithelium
- odontogenic fibroma
- odontogenic myxoma / myxofibroma
- cementoblastoma
Bone-related lesions
- ossifying fibromas (cemento-ossifying fibroma)
- fibrous dysplasia
- osseous dysplasias
- central giant cell lesion (granuloma)
- cherubism
- aneurysmal bone cyst
- simple bone cyst
Other tumours
-<li><a href="/articles/florid-cemento-osseous-dysplasia">florid cemento-osseous dysplasia</a></li>- +<li><a href="/articles/florid-cemento-osseous-dysplasia-1">florid cemento-osseous dysplasia</a></li>
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