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Embryonal tumor with multilayered rosettes (ETMR)

Case contributed by Frank Gaillard
Diagnosis almost certain

Patient Data

Age: child

MRI of the brain demonstrates a large heterogenous mass of the left temporal lobe with patchy regions of contrast enhancement. 

Case Discussion

This patient went on to have resection which confirmed the diagnosis of a supratentorial PNET

Note: The current (2016) WHO classification of CNS tumors has made substantial changes to tumors previously considered to be supratentorial PNET, now classified as embryonal tumors with multilayered rosettes (ETMR), along with a number of other entities, in recognition of characteristic amplification of the C19MC region on chromosome 19 (19q13.42).

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