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CT of the chest was performened on the same day as the 2nd CXR 2 days after starting ATRA Rx for APL.
Diffuse mixed consolidated and ground glass infiltrates are present. Minimal cardiomegaly. Small bilateral pleural effusions.
This pattern may be due to pulmonary edema of cardiac origin, non-cardiogenic pulmonary edema, or other entities such as diffuse pulmonary hemorrhage. Considering this patient's recent ATRA therapy, the pulmonary edema pattern is most likely due to the Differentiation Syndrome (ATRA syndrome).