Apical lung tumour
High-grade large-cell undifferentiated carcinoma located in the apical segment and measuring 2.5 cm in maximum dimension showing radiation/chemotherapy effect. Tumour extends into the overlying chest wall. The tumour is almost entirely necrotic with only small islands of viable tumour cells remaining, (approximately 10% of the tumour appears viable).
Surrounding lung parenchyma shows changes consistent with chemotherapy and radiation, namely interstitial fibrosis, intimal fibrosis and inflammation of the interstitium.
Prominent centrilobular emphpysema is present with subpleural blebs and bullae.