Bone marrow infiltrative disease (leukemia)
Updates to Case Attributes
**LeukemiaLeukemia includes a heterogeneous group of neoplasms that infiltrate bone marrow with mature or immature cells of the white blood cell lineage. In leukemia, bone marrow infiltration usually occurs diffusely, with a diffuse decrease in the marrow signal intensity onT1-weighted image images. MRI is highly sensitive for detecting bone marrow infiltration, but its specificity is poor, leaving the diagnosis of leukemia to peripheral blood smears and bone marrow biopsy.
** T1- weighted imaging is the most sensitive pulse sequence to assess abnormal bone marrow signal intensity.
-<p>**Leukemia includes a heterogeneous group of neoplasms that infiltrate bone marrow with mature or immature cells of the white blood cell lineage. In leukemia, bone marrow infiltration usually occurs diffusely, with a diffuse decrease in the marrow signal intensity on<em> T1-weighted image </em>. MRI is highly sensitive for detecting bone marrow infiltration, but its specificity is poor, leaving the diagnosis of leukemia to peripheral blood smears and bone marrow biopsy.</p><p>** T1- weighted imaging is the most sensitive pulse sequence to assess abnormal bone marrow signal intensity.</p>- +<p>Leukemia includes a heterogeneous group of neoplasms that infiltrate bone marrow with mature or immature cells of the white blood cell lineage. In leukemia, bone marrow infiltration usually occurs diffusely, with a diffuse decrease in the marrow signal intensity on<em> </em>T1-weighted images. MRI is highly sensitive for detecting bone marrow infiltration, but its specificity is poor, leaving the diagnosis of leukemia to peripheral blood smears and bone marrow biopsy.</p><p>T1 weighted imaging is the most sensitive pulse sequence to assess abnormal bone marrow signal intensity.</p>
Updates to Study Attributes
Diffuse replacement of the normal bone marrow signal intensity of examined parts of the skeleton
( lower(lower lumber spines, sacrum, pelvic bones and bothfemorifemora).- It displaysdiffuse low signal intensity on T1WI, heterogeneous high signal intensity on T2WIwith no signal suppression onT2 fat sat indicating of reconversion or infiltration of yellow bone marrow.
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