Chronic myeloid leukemia

Case contributed by Dr Maxime St-Amant


Lumbar pain back pain without recent trauma.

Patient Data:

Age: 75
Gender: Female
Modality: MRI

On T1, the bone structures are abnormally diffusely hypointense, compatible with an infiltrative bone marrow disease. In this case, the patient was known for a chronic myeloid leukemia, which explains the findings.

Case Discussion:

There is widespread low T1 signal throughout the vertebral bodies with accompanying T2 hyperintensity and several vertebral compression fractures.

Diffuse homogeneous signal abnormalities can easily be missed and assessment of marrow should be a review area.

The diagnosis here is chronic myeloid leukaemia but can seen in other cause of bone marrow infiltration.

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