Congenital cytomegalovirus infection

Case contributed by Ahmed Abdrabou
Diagnosis almost certain

Presentation

New born with scalp swelling and weak cry.

Patient Data

Age: 1 day old
Gender: Male

Extensive periventricular, basal ganglionic and parenchymal calcification with hydrocephalic changes and parenchymal atrophy

Diagnosis: CMV encephalitis

Case Discussion

Transplacental spread of cytomegalovirus results in congenital CMV infection which has variable appearance according to the time of infection, however periventricular, basal ganglionic and parenchymal calcification together with migrational abnormalities are all common features.

The congenital infections are known as TORCH.

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