Craniopharyngioma

Microscopic description

The section shows a single small fragment of tissue. This is
composed of irregularly shaped islands of mature squamous epithelium
which are dispersed in a loose fibrous stroma. These show strong
immunostainign for cytokeratins AE1/AE3 and CAM5.2. The stroma contains aggregates of keratin. Focal foreign-body type granulomatous
inflammation in association with some collections of keratin are
noted. There is also focal dystrophic calcification. No cyst formation
is seen. The features are those of a carniopharyngioma.