Ewing sarcoma
Presentation:
Right hip pain worsening over the last 6 months.
Patient Data:
AP pelvis
The right iliac bone demonstrates an ill-defined lytic lesion, with a wide zone of transition. The medial part of the acetabular cortex is poorly seen, potentially representing extension into the joint. In addition there is some fullness and increased density of the soft tissues immediately medial to this region within the pelvis, suggesting extension beyond the bone. There are smaller patchy translucencies of the right proximal femur, the inferior pubic ramus and the tuber ischii, as well.
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T1
Coronal
Multiple intramedullary bone lesions involving both femora and the pelvis bilaterally. Evidence of bilateral acetabular bone involvement with expansion and a soft-tissue component which is more prononced on the right, extending both posterolateral to the bone (into the gluteus musculature) and medially (into the pelvis).
Permeative and lytic lesion predominantly around the right acetabulum is demonstrated with multiple other lesions seen in the axial and appendicular skeleton. CT reviewed in on other window settings demonstrated no convincing solid organ metastases.
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Blood flow (bone scan)
The flow and blood pool images of the pelvis show moderate increased tracer uptake involving both hip joint regions, more pronounced on the right side indicating evidence of hyperemia.
On total body skeletal images, the skull shows multiple foci of heterogeneous and diffuse tracer uptake with a focal more intense uptake involving the left orbital ridge most likely metastatic in nature. Further diffuse and heterogeneous uptake (likely metastatic deposits) in:
- multiple ribs on both sides
- both scapula
- both humeri
- right iliac bone
- both acetabulum/ischium
- left iliac crest
- both femora
Multiple vertebral bodies in the thoracolumbar region also show heterogeneouc moderate tracer uptake worrisome for metastasis.
A CT guided bone biopsy confirmed Ewing sarcoma as the primary diagnosis.
Case Discussion:
This case demonstrates the features of very widespread bony disease from Ewings sarcoma of the pelvis.
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