Ganglioglioma of the optic nerve

Case Description

Histology

MACROSCOPIC DESCRIPTION:

"Brain tissue": Five fragments of tan coloured tissue measuring up to
3mm in maximum dimension.

MICROSCOPIC DESCRIPTION:

The sections show a moderately hypercellular tumour composed of mature ganglion cells, some of which are binucleated. These are mixed with astrocytic cells showing a mild degree of nuclear pleomorphism. The ganglion cells show strong immunostaining for chromogranin,
synaptophysin and neurofilament protein (NFP). No mitotic figures,
vascular endothelial cell hyperplasia or necrosis are identified. The
features are of ganglioglioma.

DIAGNOSIS:

Ganglioglioma (WHO Grade 2).

1 Article features images from this Case

T2

ModalityMRI

  • MRI: T2 . Case Ganglioglioma of the optic nerve

    T2

  • MRI: T1 . Case Ganglioglioma of the optic nerve

    T1

  • MRI: T1 C+ . Case Ganglioglioma of the optic nerve

    T1 C+

  • MRI: T1 . Case Ganglioglioma of the optic nerve

    T1

  • MRI: T1 C+ . Case Ganglioglioma of the optic nerve

    T1 C+

  • MRI: T1 . Case Ganglioglioma of the optic nerve

    T1

  • MRI: FLAIR . Case Ganglioglioma of the optic nerve

    FLAIR

  • MRI: T2 . Case Ganglioglioma of the optic nerve

    T2

  • MRI: T1 C+ . Case Ganglioglioma of the optic nerve

    T1 C+

  • MRI: DWI . Case Ganglioglioma of the optic nerve

    DWI

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