Giant cell granuloma - mandible

Case contributed by Dayu Gai
Diagnosis possible

Presentation

Right jaw pain.

Patient Data

Age: 15 years
Gender: Female
x-ray

Lytic lesion of mandibular ramus centered over the retromolar trigone may be consistent with giant cell granuloma.

Case Discussion

Giant cell granulomas are benign intraosseous lesions, typically occurring in young females. They result from a local inflammatory process, thought to be secondary to trauma. Due to these lesions often being symptomatic, active management is usually performed. Non surgical treatment may include:

  • intralesional corticosteroid injection
  • subcutaneous calcitonin injection

The more "aggressive" giant cell granulomas are treated with either surgical resection or curettage. Nevertheless, recurrence rates are high and quoted to be between 11-49% 1.

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