Glioblastoma - multifocal

Case contributed by A.Prof Frank Gaillard

Patient Data:

Age: Adult

CT Brain

Modality: CT

to be added

MRI Brain

Modality: MRI

to be added

Case Discussion:

Multifocal / multicentric GBM

Final Diagnosis: Temporal lobe lesion: Glioblastoma.

Microscopic Description: Sections show a densely cellular glial neoplasm. The tumour cells have hyperchromatic, pleomorphic nuclei and abundant eosinophilic cytoplasm with fibrillary processes. There are areas where the tumour cells have scant cytoplasm and round nuclei that could represent focal oligodendroglial differentiation. Mitotic figures are frequent and there is abundant endothelial proliferation and tumour necrosis with pseudopalisading.

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