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Hypoxic ischemic encephalpathy

Case contributed by Ahmed Abdrabou
Diagnosis almost certain

Presentation

Delayed mental and motor milestones. History of NICU admission after prolonged delivery

Patient Data

Age: 2 years old
Gender: Male

Abnormal signal intensity is detected at the periventricular deep white matter (coronal radiata and centrum semiovale) bilaterally dispalying bright signal in T2 and FLAIR and low signal in T1 and T1 inversion recovery. There is no mass effect and with sparing of the subcortical U fibers, corpus callosum and brain stem.

Case Discussion

Cerebral hypoperfusion injury usually affects the watershed zones and should be differentiated from other white matter diseases e.g. leukodystrophies and congenital infection.

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