Colonoscopy revealed a lumen occluding
circumferential proliferative growth in the descending colon.
Microscopic Description:Section shows fragments of large intestinal
mucosa containing part of an ulcerating neoplasm with villous architecture in
places lined by cells displaying nuclear crowding, stratification and
hyperchromasia, variably conspicious nucleoli and frequent mitosis.
Disorganised glands with luminal necrosis and moderate to severe degree of
cytological atypia and apical mitosis are present in the lamina propria and
also between muscularis mucosal fibres. There is associated inflammation and
Colonic biopsy conclusion: Moderately
differentiated colon adenocarcinoma.