Leptomeningeal carcinomatosis with moderate hydrocephalus and calvarial metastases

Case contributed by Mohammad A. ElBeialy
Diagnosis probable

Presentation

History of breast cancer post MRM and chemoradiotherpay. Now presenting with delirium and disturbed level of conciousness as well as vomiting and urine incontinence for 2 months.

Patient Data

Age: 50 years
Gender: Female
  • diffuse leptomeningeal enhancement with hyperintense FLAIR signal seen smearing the cortical sulci as well as the basal cisterns.
  • moderate supratentorial hydrocephalus with transependymal interstitial CSF permeation.
  • altered marrow signal of the skull base and calvarial bones with hypointense T1 and T2 signal with heterogeneous post-contrast enhancement.   

Case Discussion

Leptomeningeal carcinomatosis and moderate hydrocephalus as well as calvarial matastases.

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