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Lung metastases from uterine sarcoma

Case contributed by Dr Bruno Di Muzio


Patient with uterine leiomyosarcoma follow-up.

Patient Data:

Age: 77
Gender: Female

Chest X-ray

Modality: X-ray

Large pulmonary nodules distributed in the left lung.

CT Chest

Modality: CT

Large pulmonary nodules distributed in the left lung.

Case Discussion:

This case illustrates metastatic disease to the lungs. The abdomen and pelvis CT did not demonstrate para-aortic or intraperitoneal involvement. 

Uterine sarcoma metastasis ere demonstrated to most frequently involve the peritoneal cavity and omentum (~60%), followed by the lung (~50%), pelvic lymph nodes (~40%), para-aortic lymph nodes (38%), and liver parenchyma (34%) 1

The study showed also that the presence of lung metastasis was not associated with pelvic or para-aortic nodes metastasis or intraperitoneal disease. Metastasis to other distant sites including the brain, heart, kidney, and bone were independent of pelvic and para-aortic nodal metastasis or intraperitoneal disease 1.

Hematogenous metastasis best explains this metastatic pattern 1.

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