Malignant oligodendroglioma

Case contributed by A.Prof Frank Gaillard

Patient Data:

Age: adult
Modality: MRI

Right high frontal intra axial lesion with marginal enhancement

Case Discussion:

Final Diagnosis: 

Brain, right frontal: Malignant oligodendroglioma

Microscopic Description:

Sections show brain tissue infiltrated by a glial tumor that displays oligodendroglial features. Tumor infiltration into adjacent brain tissue is represented by subpial infiltration, focally prominent neuronal satellitosis and linear profiles of tumor cells. Perivascular infiltration by tumor cells is also observed. In the more cellular areas the tumor cells display characteristic oligodendroglial features. Mitotic activity is increased in areas. Very focal vascular neogenesis is noted, represented by focal proliferation of endothelial cells. Tumour necrosis is not seen.

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