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Osteogenesis imperfecta

Case contributed by Dr Hani Salam
Modality: X-ray

Case Discussion:

Multiple x-rays of a child demonstrating wide spread abnormalities. 

The skull demonstrates prominent wormian bones, and platybasia

The long bones demonstrate numerous horizontal lines (so called zebra stripes) associated with cyclical bisphosphonate therapy. Additionally, a number of united fractures are noted, particularly of the femurs and left tibia. 

Features are consistent with osteogenesis imperfecta

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