Osteogenesis imperfecta and bisphosphonate lines

Case contributed by Dr Michael Sargent

Patient Data

Age: 10 months
Gender: Female
Modality: X-ray

Osteopaenic, gracile bones with zebra stripes. Evidence of prior right femoral fracture. 

Case Discussion

Baby girl with type II osteogenesis imperfecta, treated with cyclical bisphosphonate therapy (pamidronate) resulting in the "zebra stripe sign". Also note the wormian bones on the skull x-ray.

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Case Information

rID: 6037
Diagnostic certainty: Certain
Inclusion in quiz mode: Included

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