Pituitary macroadenoma with necrosis
Case contributed by:
Dr Frank Gaillard
Presentation:
Visual disturbance.
Patient Data:
Age: Adult
Gender: Male
Race: Caucasian
Loading more images...
T1
This patient went on to have a transphenoidal resection.
Histology
Most of the tissue fragments are composed of uniform cells with round nuclei and abundant granular cytoplasm arranged in solid sheets and papillary structures. Rare mitotic figures are identified. Small fragments of atrophic adenohypophysis are also present. Immunohistochemistry for pituitary hormones shows the tumor to have moderately intense, focal positivity for LH.
Final diagnosis: pituitary adenoma (focal reactivity for LH).
Case Discussion:
Although most macroadenomas are solid, cystic change due to necrosis or prior haemorrhage is not infrequently seen.
Related articles
Details successfully updated.
Unable to process the form. Check for errors and try again.