Presentation
Sudden onset cortical blindness.
Patient Data
Note: This case has been tagged as "legacy" as it no longer meets image preparation and/or other case publication guidelines.
T2 and FLAIR images show high signal intensities in both occipital lobes. Interestingly DWI and ADC map demonstrate a focal area of restricted diffusion in the splenium of corpus callosum. No restricted diffusion seen in the occipital lobes. No enhancement demonstrated on the post-contrast T1 examination.
MRI TOF and venogram are both unremarkable.
Case Discussion
The coexistence of PRES and restricted diffusion in the splenium of corpus callosum highlights the potential possibility of vasoconstriction of the pericollasal branches supplying the splenium arising from the posterior cerebral artery.
Unfortunately, no follow-up imaging was performed to document if these changes were transient, but reversible splenial lesion has been reported to be associated with a wide range of etiologies, however is extremely rare in the setting of PRES.