Severe osteoporosis - end-stage renal disease

Case contributed by Mohammad Taghi Niknejad
Diagnosis almost certain

Presentation

End-stage renal disease. Long-standing hemodialysis.

Patient Data

Age: 35 years
Gender: Male

Severe uneven decreased bone density with cortical thinning. Widespread areas of lucency in both lower limbs are present with resulting deformities. 

Case Discussion

This case demonstrates severe osteoporosis in a patient with end-stage renal disease and long-standing hemodialysis. Patients with end-stage renal disease are susceptible to a constellation of skeletal abnormalities related to renal osteodystrophy, as well as osteopaenia1. Fracture rate is also higher in patients undergoing dialysis. 

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