895 results found
Article
Hereditary spherocytosis
Hereditary spherocytosis (HS) (also known as Minkowski-Chauffard disease 1) is a group of hemolytic anemias due to a genetic abnormality of the erythrocyte cell membrane resulting in spherocytes. The clinical spectrum is broad, from a subclinical state to severe transfusion-dependant anemia.
Ep...
Article
Sinusoidal obstruction syndrome
Sinusoidal obstruction syndrome (SOS), previously known as hepatic veno-occlusive disease (VOD), is a condition arising from occlusion of hepatic venules.
Clinical presentation
right upper quadrant pain
painful hepatomegaly
ascites
abnormal liver function tests
Pathology
Toxic injury to l...
Article
Normal gastrointestinal tract imaging examples
This article lists examples of normal imaging of the gastrointestinal tract and surrounding structures, divided by modality.
Plain radiograph
abdominal film
example 1
example 2: erect and supine
example 3: pediatric
example 4: pediatric
example 5: young adult male
Barium studies
barium ...
Article
Splenic metastases
Splenic metastases are relatively rare on imaging and are more commonly encountered at autopsy. Typically they are part of a widespread metastatic disease.
Epidemiology
The rate of splenic metastases varies between 1-10% of autopsy studies, depending on whether microscopic or macroscopic metas...
Article
Hemoglobinopathies
A hemoglobinopathy is a genetic disorder which alters the structure of hemoglobin 1. The result is reduced oxygen-carrying capacity of the blood to the tissues, and other sequelae.
Clinical presentation
Clinical presentation varies, is related to hypoxia, and characteristically includes the fo...
Article
Splenic abscess
Splenic abscesses, like abscesses elsewhere, are localized collections of necrotic inflammatory tissue caused by bacteria, parasites or fungi. They uncommonly affect the spleen due to its efficient reticuloendothelial system phagocytic activity and, consequently, are more likely seen in immunosu...
Article
Bone marrow
Bone marrow is ubiquitous throughout the skeleton, primarily composed of hematopoietic cells and fat cells between bony trabeculae and fibrous retinacula. It performs numerous physiological functions and dynamically changes during normal aging and in response to stressors and pathology. Although...
Article
Heparin-induced thrombocytopenia
Heparin-induced thrombocytopenia (HIT) is a paradoxical thrombotic state resulting from an immune response to heparin, although the condition can rarely occur without heparin exposure.
Terminology
Heparin-induced thrombocytopenia and immune thrombocytopenia (ITP) are unrelated conditions.
Epi...
Case
Splenomegaly
Published
28 Oct 2017
50% complete
X-ray
Article
Leishmaniasis
Leishmaniasis refers to zoonoses caused by parasites of the genus Leishmania. There are three main forms of leishmaniasis:
visceral (also known as kala-azar or dum-dum fever)
cutaneous
mucocutaneous leishmaniasis
Epidemiology
Leishmaniasis is a truly global disease with a higher burden in t...
Case
Extramedullary hematopoiesis
Published
09 Feb 2024
95% complete
MRI
Case
Acute lymphoblastic leukemia
Published
26 May 2016
87% complete
Photo
Ultrasound
X-ray
MRI
Case
Multiple myeloma
Published
04 Aug 2020
95% complete
X-ray
CT
Case
Ruptured splenic hydatid cyst
Published
01 Jan 2016
92% complete
CT
Article
Ommaya reservoir
Ommaya reservoir, also known as Ommaya shunt, is a device for repetitive access to the intrathecal space, consisting of an intraventricular catheter connected to a reservoir (port) implanted beneath the scalp. It is used for intrathecal administration of medication such as chemotherapy (mainly i...
Article
Splenic artery embolization
Splenic artery embolization is an endovascular technique for treatment of splenic and splenic artery pathology as an alternative to splenic artery ligation or splenectomy. It often results in successfully treating the underlying pathology, while maintaining at least partial splenic function.
I...
Case
AIDS-related lymphomatosis
Published
10 Apr 2018
77% complete
CT
Article
Erythrocyte sedimentation rate
Erythrocyte sedimentation rate (ESR) is a non-specific marker of acute inflammation which is seen in a very wide spectrum of pathologies. It has been sidelined by the use of C-reactive protein and other acute phase markers but it still has an important role to play in the management of some cond...
Article
All-trans-retinoic acid syndrome
All-trans-retinoic acid (ATRA) syndrome, is the more common cause of differentiation syndrome 8. Acute promyelocytic leukemia (APL) cells respond to therapeutic levels of this normal plasma derivative of vitamin A by maturating into normal granulocytes which can cause capillary leakage and organ...
Article
Twin anemia polycythemia sequence
Twin anemia polycythemia sequence (TAPS) is considered a variant of the twin to twin transfusion syndrome (TTTS) occurring in monochorionic twin pregnancies.
Epidemiology
TAPS may occur spontaneously in up to 5% of monochorionic twins and may also develop after incomplete laser treatment in tw...
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