Articles

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1,118 results found
Article

Intraparotid nodal metastases

Intraparotid nodal metastases refer to metastatic involvement of intraparotid lymph nodes from either a primary parotid tumor or an extraparotid tumor in the head and neck (e.g. nasopharyngeal carcinoma). Pathology Location There may be a predilection towards the superficial lobe or tail regi...
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Fibrosing inflammatory pseudotumor

Fibrosing inflammatory pseudotumors are an inflammatory process with histology showing a polymorphous infiltrate with plasma cells, lymphocytes and eosinophils as well as a significant reactive fibrovascular component. Pathology Location They can occur at various sites of the body including: ...
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Peripheral T cell lymphoma

Peripheral T cell lymphoma is an uncommon, heterogeneous group of lymphoma. It can account for around 5-15% of non-Hodgkin lymphoma (NHL). Terminology The word "peripheral" does not mean involvement in the extremities but refers to tumor cells that arise from lymphoid tissue outside of the bon...
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Adrenal lymphoma

Adrenal lymphoma can refer to: primary adrenal lymphoma: rare  can be bilateral in around 70% of cases 1 secondary involvement of the adrenal glands with lymphoma: more common Clinical presentation The presentation can be variable and may include adrenal insufficiency, worsening general sta...
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Thymic hyperplasia

Thymic hyperplasia is a disorder whereby there is hyperplasia of the thymus. Pathology Thymic hyperplasia can be subdivided into two forms:  true thymic hyperplasia lymphoid thymic hyperplasia Both true thymic hyperplasia and lymphoid hyperplasia manifest as diffuse symmetric enlargement of...
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International Myeloma Working Group response criteria

The International Myeloma Working Group response criteria are consensus definitions used to assess response to treatment of multiple myeloma. With the latest version published in 2016, the criteria have been widely adopted for classifying responses in clinical trials and in routine practice 1. I...
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Leiomyoma

Leiomyoma is a benign smooth muscle (myometrial) tumor, most commonly found in the uterus.  Classification Leiomyoma is classified by location: uterine leiomyoma cervical leiomyoma leiomyoma of the urinary bladder urethral leiomyoma solitary cutaneous leiomyoma vascular leiomyoma (angiol...
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Tumor lysis syndrome

Tumor lysis syndrome (TLS) is an entity representing a constellation of laboratory and clinical derangements inclusive of: hyperuricemia hyperphosphatemia hypocalcemia and hyperkalemia It is considered an oncological emergency and can occur following treatment of malignancies with high cell...
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Pseudo Meigs syndrome

Pseudo Meigs syndrome refers to a clinical syndrome of pleural effusion and ascites associated with an ovarian tumor that is not a fibroma or a fibroma-like tumor. Pathology Entities that have been reported to result in pseudo Meigs syndrome include Krukenberg tumors colon carcinoma metastas...
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Gallbladder cancer (staging - AJCC 8th edition)

The AJCC (American Joint Committee on Cancer) 8th edition gallbladder cancer staging system was introduced in 2018. TNM system T: primary tumor Tis: carcinoma in situ - tumor only within the epithelium (the inner layer of the gallbladder) T1: tumor invades the lamina propria or muscularis T...
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Preinvasive lesions of the lung

Preinvasive lesions of the lung are those pulmonary lesions that have not yet progressed to malignancy but have the potential to do so. This category includes: squamous dysplasia (SD) of lungs: squamous cell carcinoma in situ (CIS) of lung preinvasive adenocarcinoma of the lung 5,6 atypical a...
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Peripheral intermediate and high-grade chondrosarcoma

Peripheral chondrosarcomas grade 2 and 3 are malignant intermediate and high-grade chondrogenic neoplasms originating from the bony surface in the chondral cap of pre-existing osteochondromas as a result of malignant transformation, thus the name secondary peripheral chondrosarcoma 1,2. Secondar...
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Mesothelioma

Mesothelioma, also known as malignant mesothelioma, is an aggressive malignant tumor of the mesothelium. Most tumors arise from the pleura, and so this article will focus on pleural mesothelioma. Given the presence of the mesothelium in different parts of the body, mesothelioma can arise in var...
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Primary pleural lymphoma

Primary pleural lymphoma is extremely rare, especially in immunocompetent patients. Epidemiology Primary pleural lymphoma accounts for <0.5% of all non-Hodgkin lymphoma 2 and ~2.5% of primary chest wall tumors 4.  Pathology Primary pleural lymphoma may be Hodgkin or non-Hodgkin lymphoma with...
Article

Periosteal reaction

Periosteal reaction is a nonspecific radiographic finding that indicates new bone formation in reaction to the abnormal stimulants. Periosteal reactions may be broadly characterized as benign or aggressive, or more specifically categorized by pattern. Terminology Periosteal reaction is the rec...
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Pleural metastases

Pleural metastases account for the vast majority of malignant lesions of the pleura and are more common than malignant mesothelioma. Clinical presentation The infiltration of the pleura usually manifests as pleural effusion, which is the first manifestation of pleural metastasis. In addition t...
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Wilms tumor (staging)

Wilms tumor staging is largely anatomical and relates to the invasion and spread of the tumor. Where there is invasion or metastasis, prognosis is poorer. Wilms tumor is one of the more common childhood malignancies. stage I confined to kidney complete resection possible stage II local spre...
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Chronic myelomonocytic leukemia

Chronic myelomonocytic leukemia (CMML) is a relatively rare clonal hematologic disorder. In the World Health Organizatiοn classification, it is listed as a disorder with features of both myelodysplastic syndromes and myeloproliferative neoplasms. Clinical presentation Can be variable but many ...
Article

Transitional cell carcinoma (staging)

Staging of transitional cell carcinomas of the urinary tract vary according to the location of the tumor, and are staged using the TNM staging system.  transitional cell carcinoma of the renal pelvis transitional cell carcinoma of the ureter transitional cell carcinoma of the bladder  
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Basal cell carcinoma of the prostate

Basal cell carcinoma of the prostate or prostatic adenoid basal proliferation of uncertain significance is a type of prostate cancer resembling adenoid cystic carcinoma of the salivary glands. Terminology Other terms include 'adenoid cystic carcinoma', 'adenoid basal cell tumor', 'adenoid cyst...

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