895 results found
Article

Hematopoietic stem cell transplantation (abdominal complications)

Abdominal complications of hematopoietic stem cell transplantation can occur early (0-100 days) or late (>100 days) post-transplant.  Complications Early bacterial infections, e.g. pseudomembranous colitis fungal infections, often affecting the esophagus or as hepatic/splenic microabscesses ...
Article

Primary bone lymphoma

Primary bone (skeletal/osseous) lymphoma (PBL) is a less common manifestation of lymphoma than secondary involvement from disseminated lymphoma. It is rare, accounting for <5% of bone tumors and <1% of non-Hodgkin lymphoma. Terminology PBL is defined as the presence of lymphoma isolated to one...
Case

Thalassemia - skull

  Diagnosis almost certain
Dalia Ibrahim
Published 13 Jul 2022
77% complete
CT
Case

Gaucher's disease - splenic Gaucheroma

  Diagnosis certain
Liz Silverstone
Published 12 Aug 2021
91% complete
Ultrasound CT Nuclear medicine X-ray
Article

Anemia of chronic disease

Anemia of chronic disease, also known as anemia of inflammation, is a type of anemia caused by chronic inflammation.  Terminology According to some sources, the term 'anemia of inflammation' should replace, or has already replaced, the terms 'anemia of chronic disease' and 'anemia of chronic d...
Case

Multiple myeloma - right proximal femur

  Diagnosis almost certain
Henry Knipe
Published 01 Mar 2022
77% complete
CT
Article

Hemolytic uremic syndrome

Hemolytic uremic syndrome (HUS) is a multisystem thrombotic microangiopathic disease characterized by the triad of renal failure, hemolytic anemia and thrombocytopenia. It is the most common cause of renal failure in infancy and childhood requiring dialysis.  There are two forms of this syndrom...
Case

Hodgkin lymphoma

  Diagnosis almost certain
James Sheldon
Published 13 Jan 2014
77% complete
CT
Article

Mediastinal lymph node enlargement

Mediastinal lymph node enlargement can occur from a wide range of pathologies and can be isolated or associated with lung pathology. Historically, a size cut-off of 10 mm short-axis diameter was used.  Terminology The term mediastinal lymphadenopathy implies lymph node disease and is not synon...
Case

Anaplastic large cell lymphoma - ALK positive subtype

  Diagnosis almost certain
Ammar Haouimi
Published 09 Jan 2023
77% complete
MRI
Article

AIDS-defining illness

AIDS-defining illnesses are conditions that in the setting of a HIV infection confirm the diagnosis of AIDS and do not commonly occur in immunocompetent individuals 2. According to the CDC surveillance case definition 1, they are: Infectious bacterial infections: multiple or recurrent ca...
Article

Hyperimmunoglobulin IgE syndrome

Hyperimmunoglobulin E (hyper IgE) syndrome (HIES), also known as Job syndrome, consists of a heterogeneous group of complex hereditary combined B- and T-cell immune deficiency diseases characterized by recurrent Staphylococcus aureus chest infections, characteristic coarse facial appearance and ...
Article

Pyrexia of unknown origin

A pyrexia of unknown origin, commonly shortened to PUO, and also known as a fever of unknown origin (FUO), was originally defined in 1961 as the condition in which the core body temperature is >38.3oC for a period of three weeks or more, with no diagnosis reached after one week of inpatient inve...
Case

Thrombosis of bilateral iliocaval stents

  Diagnosis almost certain
Chandler Sloan Fane
Published 05 Aug 2022
80% complete
CT
Article

Cyanosis

Cyanosis (plural: cyanoses) is a physical sign represented by bluish discolouration of the skin. It indicates there is reduced oxygen bound to red blood cells in the bloodstream. Diagnosis of the underlying cause of cyanosis is based on a thorough history and physical examination. Pathology Et...
Case

Mediastinal lymphoma

  Diagnosis certain
Mahomed A. Osman
Published 19 Mar 2013
86% complete
X-ray CT
Case

Humeral head and femoral head osteonecrosis due to sickle cell disease

  Diagnosis certain
Yaïr Glick
Published 09 Dec 2021
91% complete
X-ray
Article

Trousseau syndrome

Trousseau syndrome is an inconsistently defined entity which broadly represents the association between thromboembolism and malignancy, often prior to or concomitantly with the diagnosis of the underlying malignancy 1. The syndrome has been variably defined to include entities such as migratory...
Article

Idiopathic hypereosinophilic syndrome

Idiopathic hypereosinophilic syndrome (IHES) is a leukoproliferative disorder and refers to a situation when there is an unexplained prolonged eosinophilia with associated organ system dysfunction.  Pathology Individuals have prolonged raised total leukocyte counts with raised eosinophil count...
Article

Sézary syndrome

Sézary syndrome (SS) is a type of primary cutaneous T-cell lymphoma.  Clinical presentation It is clinically characterized by an extensive erythematous rash covering most of the body as well as the presence of malignant lymphocytes in the blood. History and etymology It is named after Albert...

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.