901 results found
Case

CT guided sacral bone biopsy - Hodgkin lymphoma

  Diagnosis certain
Bruno Di Muzio
Published 07 Jan 2016
89% complete
CT MRI Nuclear medicine
Article

Heparin-induced thrombocytopenia

Heparin-induced thrombocytopenia (HIT) is a paradoxical thrombotic state resulting from an immune response to heparin, although the condition can rarely occur without heparin exposure. Terminology Heparin-induced thrombocytopenia and immune thrombocytopenia (ITP) are unrelated conditions. Epi...
Case

Leukemic infiltration of the optic nerve

  Diagnosis almost certain
Ali Hekmatnia
Published 05 Jun 2018
80% complete
MRI
Case

Burkitt lymphoma

  Diagnosis almost certain
Henry Knipe
Published 10 Sep 2015
77% complete
CT
Case

Plasma cell myeloma

  Diagnosis certain
Hani M. Al Salam
Published 08 Aug 2010
79% complete
X-ray CT
Article

Hypogammaglobulinaemia

Hypogammaglobulinaemia is an immune disorder characterized by a reduction in all types of gammaglobulins.  Terminology While hypogammaglobulinaemia means some loss of gammaglobulins, a total loss is termed agammaglobulinaemia which can occur as an X-linked form (X-linked agammaglobulinemia). ...
Case

Splenic leishmaniasis

  Diagnosis certain
Adrià Roset Altadill
Published 19 Jan 2023
95% complete
CT
Article

Rubinstein-Taybi syndrome

Rubinstein-Taybi syndrome (RTS) is a very rare genetic multi-system disorder primarily characterized by intellectual disability, broad and often angulated thumbs and halluces, and distinctive facial features. Epidemiology The estimated incidence is 1 in 100,000-125,000 live births 5. Clinical...
Article

Hairy cell leukemia

Hairy cell leukemia is a rare and indolent form of small mature B-cell leukaemias. Epidemiology Its annual incidence is estimated at around 0.3 cases per 100 000, and the disease comprises 2-3% of all leukaemias. There is a recognized male predilection of around 4:1 with a median age of around...
Article

Hematopoietic stem cell transplantation

Hematopoietic stem cell transplantation (HSCT) (encompasses bone marrow transplantation (BMT)) is a relatively common procedure used to treat a wide spectrum of conditions 1,2: lymphoproliferative disorders, e.g. multiple myeloma (most common indication), lymphoma,  leukemia solid tumors, e.g...
Article

Antiphospholipid syndrome

Antiphospholipid syndrome (APLS) is a systemic autoimmune disorder. It is usually defined as the clinical complex of vascular occlusion and ischemic events occurring in patients with circulating antiphospholipid antibodies. Clinical presentation Antiphospholipid syndrome is characterized by ve...
Article

Hypovitaminosis K

Hypovitaminosis K (also known as vitamin K deficiency) is caused by a lack of vitamin K in the body.  Clinical presentation The main symptoms and signs are related to clotting dyscrasia as vitamin K is vital as a cofactor for the enzymatic activation of several key components of the clotting p...
Article

Hepatosplenomegaly

Hepatosplenomegaly is simply the simultaneous presence of a pathologically-enlarged liver (hepatomegaly) and spleen (splenomegaly). Pathology Etiology Infection Many infections can produce a mild concurrent enlargement of the liver and spleen. This list is by no means exhaustive. viral EBV...
Case

Splenic and adrenal metastases

  Diagnosis almost certain
Henry Knipe
Published 23 Mar 2015
71% complete
CT
Case

Adrenal extramedullary hematopoiesis

  Diagnosis certain
Doaa Khedr Mohamed Khedr
Published 16 Nov 2022
95% complete
CT
Article

Primary effusion lymphoma

Primary effusion lymphoma is a rare form of non-Hodgkin lymphoma (diffuse large B-cell lymphoma) characterized by malignant fluid accumulation in the absence of lymphadenopathy. Epidemiology Associations immunodeficiency states such as acquired immunodeficiency syndrome (AIDS) infections inc...
Article

Typhlitis

Typhlitis, also known as neutropenic colitis, is a necrotizing inflammatory condition which typically originates in the cecum and, often extends into the ascending colon, appendix or terminal ileum, by the time of presentation. In general patients are immunocompromised, usually neutropenic. Ter...
Article

Hemoglobin SC disease

Hemoglobin SC (HbSC) disease is a hemoglobinopathy, and a common variant of sickle cell disease (SCD). There is coinheritance of one HbS gene and one HbC gene, resulting in a milder phenotype than full-blown sickle cell disease. It most commonly manifests with a proliferative retinopathy. Painfu...
Article

Porphyria

Porphyrias are a group of rare metabolic diseases in which heme metabolism is altered. Epidemiology Porphyria is rare, with some forms being extremely rare. Estimates for the prevalence of the disease vary in the literature and could reflect differing geographic distribution and/or incomplete ...
Article

Red blood cells

Red blood cells (RBCs), also known as erythrocytes (or rarely haematids), are cells that carry oxygen by means of hemoglobin, and form part of the cellular component of blood as it circulates throughout the body. These extremely common cells are typically made in the bone marrow in a process cal...

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