895 results found
Case
Splenic leishmaniasis
Published
19 Jan 2023
95% complete
CT
Article
Rubinstein-Taybi syndrome
Rubinstein-Taybi syndrome (RTS) is a very rare genetic multi-system disorder primarily characterized by intellectual disability, broad and often angulated thumbs and halluces, and distinctive facial features.
Epidemiology
The estimated incidence is 1 in 100,000-125,000 live births 5.
Clinical...
Article
Hairy cell leukemia
Hairy cell leukemia is a rare and indolent form of small mature B-cell leukaemias.
Epidemiology
Its annual incidence is estimated at around 0.3 cases per 100 000, and the disease comprises 2-3% of all leukaemias. There is a recognized male predilection of around 4:1 with a median age of around...
Article
Hematopoietic stem cell transplantation
Hematopoietic stem cell transplantation (HSCT) (encompasses bone marrow transplantation (BMT)) is a relatively common procedure used to treat a wide spectrum of conditions 1,2:
lymphoproliferative disorders, e.g. multiple myeloma (most common indication), lymphoma,
leukemia
solid tumors, e.g...
Article
Antiphospholipid syndrome
Antiphospholipid syndrome (APLS) is a systemic autoimmune disorder. It is usually defined as the clinical complex of vascular occlusion and ischemic events occurring in patients with circulating antiphospholipid antibodies.
Clinical presentation
Antiphospholipid syndrome is characterized by ve...
Article
Hypovitaminosis K
Hypovitaminosis K (also known as vitamin K deficiency) is caused by a lack of vitamin K in the body.
Clinical presentation
The main symptoms and signs are related to clotting dyscrasia as vitamin K is vital as a cofactor for the enzymatic activation of several key components of the clotting p...
Article
Hepatosplenomegaly
Hepatosplenomegaly is simply the simultaneous presence of a pathologically-enlarged liver (hepatomegaly) and spleen (splenomegaly).
Pathology
Etiology
Infection
Many infections can produce a mild concurrent enlargement of the liver and spleen. This list is by no means exhaustive.
viral
EBV...
Case
Splenic and adrenal metastases
Published
23 Mar 2015
71% complete
CT
Case
Adrenal extramedullary hematopoiesis
Published
16 Nov 2022
95% complete
CT
Article
Primary effusion lymphoma
Primary effusion lymphoma is a rare form of non-Hodgkin lymphoma (diffuse large B-cell lymphoma) characterized by malignant fluid accumulation in the absence of lymphadenopathy.
Epidemiology
Associations
immunodeficiency states such as acquired immunodeficiency syndrome (AIDS)
infections inc...
Article
Typhlitis
Typhlitis, also known as neutropenic colitis, is a necrotizing inflammatory condition which typically originates in the cecum and, often extends into the ascending colon, appendix or terminal ileum, by the time of presentation. In general patients are immunocompromised, usually neutropenic.
Ter...
Article
Hemoglobin SC disease
Hemoglobin SC (HbSC) disease is a hemoglobinopathy, and a common variant of sickle cell disease (SCD). There is coinheritance of one HbS gene and one HbC gene, resulting in a milder phenotype than full-blown sickle cell disease. It most commonly manifests with a proliferative retinopathy. Painfu...
Article
Porphyria
Porphyrias are a group of rare metabolic diseases in which heme metabolism is altered.
Epidemiology
Porphyria is rare, with some forms being extremely rare. Estimates for the prevalence of the disease vary in the literature and could reflect differing geographic distribution and/or incomplete ...
Article
Red blood cells
Red blood cells (RBCs), also known as erythrocytes (or rarely haematids), are cells that carry oxygen by means of hemoglobin, and form part of the cellular component of blood as it circulates throughout the body. These extremely common cells are typically made in the bone marrow in a process cal...
Case
CT guided para-aortic lymph node biopsy
Published
10 Oct 2020
89% complete
CT
Ultrasound
Article
Blast crisis
A blast crisis or lymphoid blast crisis refers to the transition of chronic or accelerated phase chronic myeloid leukemia to acute leukemia. It is usually characterized by
≥30% blasts in the bone marrow or peripheral blood
or
development of extramedullary disease outside of the spleen
Among p...
Case
Mediastinal Hodgkin lymphoma
Published
10 Mar 2016
74% complete
X-ray
CT
Article
Primary pulmonary lymphoma
Primary pulmonary lymphomas refer to clonal lymphoid proliferation affecting the lungs without any detectable extrapulmonary involvement. It is much rarer than secondary pulmonary lymphoma and is most frequently represented by lymphoma of B-cell lineage - often marginal zone B-cell lymphoma of m...
Case
Splenomegaly
Published
28 Oct 2017
50% complete
X-ray
Case
Wandering spleen with volvulus and infarction
Published
06 Jul 2021
95% complete
CT
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