Pick bodies
Last revised by Daniel J Bell on 28 Apr 2020
Citation, DOI, disclosures and article data
Citation:
Gaillard F, Bell D, Hancox L, Pick bodies. Reference article, Radiopaedia.org (Accessed on 18 Apr 2024) https://doi.org/10.53347/rID-13147
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rID:
13147
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Disclosures:
At the time the article was created Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosures
Last revised:
28 Apr 2020,
Daniel J Bell ◉
Disclosures:
At the time the article was last revised Daniel J Bell had no recorded disclosures.
View Daniel J Bell's current disclosures
Revisions:
4 times, by
3 contributors -
see full revision history and disclosures
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Synonyms:
- Pick's bodies
Pick bodies are intracytoplasmic spherical inclusions found in Pick disease. They are composed of tau fibrils (thus Pick disease is a tauopathy) arranged in a disorderly array 1. Although tau protein is a major component a number of other protein products are present, including ubiquitin and tubulin 1,2.
References
- 1. Esiri MM, Trojanowski JQ. The neuropathology of dementia. Cambridge Univ Pr. (2004) ISBN:0521819156. Read it at Google Books - Find it at Amazon
- 2. Frangoise Gray, Charles Duyckaerts, Umberto De Girolami. Escourolle and Poirier's Manual of Basic Neuropathology. ISBN: 9780199929054
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