Uterine artery flow notching

Changed by Matt A. Morgan, 30 Jun 2019

Updates to Article Attributes

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Uterine artery flow notching refers to a phenomenon observed in uterine arterial Doppler ultrasound assessment.

Pathology

Associations

The presence of notching after 22 weeks is associated with several other conditions including adverse pregnancy outcomes. These include

Radiographic features

Doppler ultrasound

While notching can be either systolic or diastolic, it is typically seen as a trough like-like notch between the systolic and diastolic phases.

Significance

The presence of notching in late pregnancy is an indicator of increased uterine vascular resistance and impaired uterine circulation 2.

Bilateral notching is more concerning. Unilateral notching of the uterine artery on the ipsilateral side of the placenta, if the placenta is along one lateral wall (right or left) carries the same significance as bilateral notching. The presence of an early diastolic notch can however be a normal finding in a non-pregnant uterus and even in a gravid uterus, at least up to 16 weeks, but notching typically begins to disappear in the gravid uterus by 13 weeks with clearly established diastolic flow by 20 weeks 7.

  • -<li><a title="Serum AFP elevation" href="/articles/alpha-fetoprotein">increased maternal serum alpha fetoprotein (MSAFP)</a></li>
  • -</ul><h4>Radiographic features</h4><h5>Doppler ultrasound</h5><p>While notching can be either systolic or diastolic, it is typically seen as a trough like notch between the systolic and diastolic phases.</p><h4>Significance</h4><p>The presence of notching in late pregnancy is an indicator of increased uterine vascular resistance and impaired uterine circulation <sup>2</sup>. Bilateral notching is more concerning. Unilateral notching of the uterine artery on the ipsilateral side of the placenta, if the placenta is along one lateral wall (right or left) carries the same significance as bilateral notching. The presence of an early diastolic notch can however be a normal finding in a non-pregnant uterus and even in a gravid uterus, at least up to 16 weeks.</p>
  • +<li><a href="/articles/alpha-fetoprotein">increased maternal serum alpha fetoprotein (MSAFP)</a></li>
  • +</ul><h4>Radiographic features</h4><h5>Doppler ultrasound</h5><p>While notching can be either systolic or diastolic, it is typically seen as a trough-like notch between the systolic and diastolic phases.</p><h4>Significance</h4><p>The presence of notching in late pregnancy is an indicator of increased uterine vascular resistance and impaired uterine circulation <sup>2</sup>.</p><p>Bilateral notching is more concerning. Unilateral notching of the uterine artery on the ipsilateral side of the placenta, if the placenta is along one lateral wall (right or left) carries the same significance as bilateral notching. The presence of an early diastolic notch can however be a normal finding in a non-pregnant uterus and even in a gravid uterus, at least up to 16 weeks, but notching typically begins to disappear in the gravid uterus by 13 weeks with clearly established diastolic flow by 20 weeks <sup>7</sup>.</p>

References changed:

  • 7. Kennedy AM, Woodward PJ. A Radiologist's Guide to the Performance and Interpretation of Obstetric Doppler US. (2019) Radiographics : a review publication of the Radiological Society of North America, Inc. 39 (3): 893-910. <a href="https://doi.org/10.1148/rg.2019180152">doi:10.1148/rg.2019180152</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/31059392">Pubmed</a> <span class="ref_v4"></span>

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