Pineal parenchymal tumors
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was changed:
Pineal parenchymal tumours (pinealomas) comprise a group of related tumours ranging from the relatively benign to the highly malignant. This group comprises ofThere are four types in the WHO classification:
-
pineocytoma
- 14-30% of pineal parenchymal tumours 2
- mature well-differentiated tumour
- WHO grade I
-
pineal parenchymal tumour with intermediate differentiation
(PPTID)- 20-62% of pineal parenchymal tumours 2
- WHO grade II
/ III/III
-
papillary tumour of the pineal region
(PTPR)- yet to be graded but probably equivalent to WHO grade II
/ III/III 2
- yet to be graded but probably equivalent to WHO grade II
-
pineoblastoma
- 24-50% of pineal parenchymal tumours 2
- malignant, primitive tumours
- WHO grade IV
As you can tell from the proportions given above there is wide variation in the reported figures from series to series, which probably reflects the overall rarity of these tumours (and thus small series) and variability in the grading and terminology used.
Terminology
The term pinealoma was historically used to refer to both pineal parenchymal tumors and germinomas 3. This term has since fallen in popularity in the last several decades.
-<p><strong>Pineal parenchymal tumours </strong>(pinealomas) comprise a group of related tumours ranging from the relatively benign to the highly malignant. This group comprises of:</p><ul>- +<p><strong>Pineal parenchymal tumours </strong>comprise a group of related tumours ranging from the relatively benign to the highly malignant. There are four types in the <a title="WHO classification of CNS tumours" href="/articles/who-classification-of-cns-tumours-1">WHO classification</a>:</p><ul>
-<a href="/articles/pineal-parenchymal-tumour-with-intermediate-differentiation">pineal parenchymal tumour with intermediate differentiation (PPTID)</a><ul>- +<a href="/articles/pineal-parenchymal-tumour-with-intermediate-differentiation">pineal parenchymal tumour with intermediate differentiation</a><ul>
-<li>WHO grade II / III</li>- +<li>WHO grade II/III</li>
-<a href="/articles/papillary-tumour-of-the-pineal-region">papillary tumour of the pineal region (PTPR)</a><ul><li>yet to be graded but probably equivalent to WHO grade II / III <sup>2</sup>- +<a href="/articles/papillary-tumour-of-the-pineal-region">papillary tumour of the pineal region</a><ul><li>yet to be graded but probably equivalent to WHO grade II/III <sup>2</sup>
-</ul><p>As you can tell from the proportions given above there is wide variation in the reported figures from series to series, which probably reflects the overall rarity of these tumours (and thus small series) and variability in the grading and terminology used. </p><div id="gtx-trans" style="position: absolute; left: 194px; top: -4.8px;"><div> </div></div>- +</ul><p>As you can tell from the proportions given above there is wide variation in the reported figures from series to series, which probably reflects the overall rarity of these tumours (and thus small series) and variability in the grading and terminology used.</p><h4>Terminology</h4><p>The term pinealoma was historically used to refer to both pineal parenchymal tumors and germinomas <sup>3</sup>. This term has since fallen in popularity in the last several decades.</p>
References changed:
- 3. Louis D. A Half Century of Change in Diagnostic Neuropathology: From the Giants of Yore to Current Brain Tumor Classification. Hum Pathol. 2020;95:161-8. <a href="https://doi.org/10.1016/j.humpath.2019.06.006">doi:10.1016/j.humpath.2019.06.006</a> [<a href="https://www.ncbi.nlm.nih.gov/pubmed/31302204">Pubmed</a>]