Citation, DOI, disclosures and article data
Citation:
Skandhan A, Knipe H, Jones J, et al. Expanded amnion sign. Reference article, Radiopaedia.org (Accessed on 24 Apr 2024) https://doi.org/10.53347/rID-35585
Disclosures:
At the time the article was last revised Henry Knipe had the following disclosures:
- Radiopaedia Events Pty Ltd, Speaker fees (past)
- Integral Diagnostics, Shareholder (ongoing)
- Micro-X Ltd, Shareholder (ongoing)
These were assessed during peer review and were determined to
not be relevant to the changes that were made.
View Henry Knipe's current disclosures
The expanded amnion sign has been described as a poor prognostic sign in early pregnancy, suspicious though not diagnostic of failed early pregnancy. Any visible embryo that is surrounded by an amnion (visible on transvaginal ultrasound) should also have a heartbeat, regardless of crown-rump length. An absent heartbeat in this context is suspicious for early pregnancy loss.
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