4D syndrome

Changed by Jeremy Jones, 26 Aug 2021

Updates to Article Attributes

Body was changed:

4D syndrome is a term used to describe a manifestation of syndromic glucagonoma, a type of pancreatic endocrine tumour.

  • D: dermatitis 2
    • necrolytic migratory erythema - a widespread rash, tending to involve perioral and perigenital regions
    • oral rashes (angular stomatitis, cheilitis)
    • tend to resolve upon removal of the tumour
  • D: mild diabetes mellitus
  • D: deep vein thrombosis
  • D: depression - may be related to severe chronic dermatosis 2
  • -<p><strong>4D syndrome</strong> is a term used to describe a manifestation of <a title="Syndrome" href="/articles/syndrome">syndromic</a> <a href="/articles/glucagonoma">glucagonoma</a>, a type of <a href="/articles/endocrine-tumours-of-the-pancreas">pancreatic endocrine tumour</a>.</p><ul>
  • +<p><strong>4D syndrome</strong> is a term used to describe a manifestation of <a href="/articles/syndrome">syndromic</a> <a href="/articles/glucagonoma">glucagonoma</a>, a type of <a href="/articles/endocrine-tumours-of-the-pancreas">pancreatic endocrine tumour</a>.</p><ul>
  • -<strong>D: </strong><a title="Depression" href="/articles/major-depressive-disorder">depression</a> - may be related to severe chronic dermatosis <sup>2</sup>
  • +<strong>D: </strong><a href="/articles/major-depressive-disorder">depression</a> - may be related to severe chronic dermatosis <sup>2</sup>

References changed:

  • 1. Lewis R, Lattin G, Paal E. Pancreatic Endocrine Tumors: Radiologic-Clinicopathologic Correlation. RadioGraphics. 2010;30(6):1445-1464. <a href="https://doi.org/10.1148/rg.306105523">doi:10.1148/rg.306105523</a>
  • 1 .Lewis RB, Lattin GE, Paal E. Pancreatic endocrine tumors: radiologic-clinicopathologic correlation. Radiographics. 2010;30 (6): 1445-64. <a href="http://dx.doi.org/10.1148/rg.306105523">doi:10.1148/rg.306105523</a> - <a href="http://www.ncbi.nlm.nih.gov/pubmed/21071369">Pubmed citation</a><span class="auto"></span>

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.