Undifferentiated pleomorphic sarcoma of the retroperitoneum
Updates to Article Attributes
Retroperitoneal malignant fibrous histiocytomas are an uncommon tumour overall but are considered as one of the most common types of primary retroperitoneal neoplasms.
For a broad discussion of this type of a tumour, which commonly involves the extremities, please refer to the main article on malignant fibrous histiocytoma (MFH).
Epidemiology
Retroperitoneal malignant fibrous histiocytomas correspond to approximately 15% of all MFHs 3.
They occur with predominance in men.
Pathology
They are categorised as sarcomas and are often high-grade tumours.
There are six histological subtypes: storiform, pleomorphic, myxoid, giant cell, inflammatory and angiomatoid. Most metastasize and common sites include lung and lymph nodes.
Radiographic features
Imaging is not characteristic and clarification pathologically is required. Reassessment of malignant fibrous histiocytoma diagnosis in some series result in re-classification as dedifferentiated liposarcomas.
25% of cases include dystrophic calcification which is uncommon amongst the remaining primary retroperitoneal malignancies.
-<p><strong>Retroperitoneal malignant fibrous histiocytomas</strong> are an uncommon tumour overall but are considered as one of the most common types of <a href="/articles/primary-retroperitoneal-neoplasm">primary retroperitoneal neoplasms</a>. </p><p>For a broad discussion of this type of tumour, which commonly involves the extremities, please refer to the main article on <a title="Malignant fibrous histiocytoma" href="/articles/malignant-fibrous-histiocytoma">malignant fibrous histiocytoma (MFH)</a>.</p><h4>Epidemiology</h4><p>Retroperitoneal malignant fibrous histiocytomas correspond to approximately 15% of all MFHs <sup>3</sup>. </p><p>They occur with predominance in men.</p><h4>Pathology</h4><p>They are categorised as <a href="/articles/sarcoma">sarcomas</a> and are often high-grade tumours. </p><p>There are six histological subtypes: storiform, pleomorphic, myxoid, giant cell, inflammatory and angiomatoid. Most metastasize and common sites include lung and lymph nodes.</p><h4>Radiographic features</h4><p>Imaging is not characteristic and clarification pathologically is required. Reassessment of malignant fibrous histiocytoma diagnosis in some series result in re-classification as <a href="/articles/retroperitoneal-liposarcoma-2">dedifferentiated liposarcomas</a>.</p><p>25% of cases include dystrophic calcification which is uncommon amongst the remaining primary retroperitoneal malignancies.</p>- +<p><strong>Retroperitoneal malignant fibrous histiocytomas</strong> are an uncommon tumour overall but are considered as one of the most common types of <a href="/articles/primary-retroperitoneal-neoplasm">primary retroperitoneal neoplasms</a>. </p><p>For a broad discussion of this type of a tumour, which commonly involves the extremities, please refer to the main article on <a href="/articles/malignant-fibrous-histiocytoma">malignant fibrous histiocytoma (MFH)</a>.</p><h4>Epidemiology</h4><p>Retroperitoneal malignant fibrous histiocytomas correspond to approximately 15% of all MFHs <sup>3</sup>. </p><p>They occur with predominance in men.</p><h4>Pathology</h4><p>They are categorised as <a href="/articles/sarcoma">sarcomas</a> and are often high-grade tumours. </p><p>There are six histological subtypes: storiform, pleomorphic, myxoid, giant cell, inflammatory and angiomatoid. Most metastasize and common sites include lung and lymph nodes.</p><h4>Radiographic features</h4><p>Imaging is not characteristic and clarification pathologically is required. Reassessment of malignant fibrous histiocytoma diagnosis in some series result in re-classification as <a href="/articles/retroperitoneal-liposarcoma-2">dedifferentiated liposarcomas</a>.</p><p>25% of cases include dystrophic calcification which is uncommon amongst the remaining primary retroperitoneal malignancies.</p>