Submassive pulmonary embolism

Changed by David Carroll, 19 Feb 2021

Updates to Article Attributes

Body was changed:

A submassive pulmonary embolism refers to an acute pulmonary embolism with evidence of myocardial necrosis or right ventricular dysfunction in the absence of systemic hypotension. An elevation in troponin I or T provides evidence of myocardial necrosis. Right ventricular dysfunction is defined by the presence of any of the following: 

  • echocardiographic evidence of right ventricular dilation or systolic dysfunction
  • an RV/LV diameter ratio >0.9 on CT 4
  • biomarker elevations
    • brain natiureticnatriuretic peptide (BNP) > 90 pg/mL or pro-BNP >500 pg/mL
  • characteristic electrocardiographic abnormalities
    • right bundle branch block (complete or incomplete)
    • anteroseptal ST-T segment deviation
    • anteroseptal T wave abnormalitiesinversion

Differential diagnosis

  • -<li>echocardiographic evidence of right ventricular dilation or systolic dysfunction</li>
  • +<li>echocardiographic evidence of right ventricular dilation or <a title="RV dysfunction" href="/articles/right-ventricular-dysfunction">systolic dysfunction</a>
  • +</li>
  • -<li>biomarker elevations<ul><li>brain natiuretic peptide (BNP) &gt; 90 pg/mL or pro-BNP &gt;500 pg/mL</li></ul>
  • +<li>biomarker elevations<ul><li>brain natriuretic peptide (BNP) &gt; 90 pg/mL or pro-BNP &gt;500 pg/mL</li></ul>
  • -<li>right bundle branch block</li>
  • -<li>anteroseptal ST-T wave abnormalities</li>
  • +<li>right bundle branch block (complete or incomplete)</li>
  • +<li>anteroseptal ST segment deviation</li>
  • +<li>anteroseptal T wave inversion</li>
  • -</ul><h4>Differential diagnosis</h4><ul><li>
  • -<a title="Massive pulmonary embolism" href="/articles/massive-pulmonary-embolism">massive pulmonary embolism</a><ul><li>acute pulmonary embolism with either <a href="/articles/right-ventricular-dysfunction">right ventricular dysfunction</a> or evidence of myocardial necrosis with systemic hypotension, pulselessness or bradycardia</li></ul>
  • -</li></ul>
  • +</ul><h4>Differential diagnosis</h4><ul>
  • +<li>
  • +<a href="/articles/massive-pulmonary-embolism">massive pulmonary embolism</a><ul><li>associated with sustained hypotension, bradycardia with signs of shock, or pulselesness</li></ul>
  • +</li>
  • +<li>right ventricular <a title="Myocardial infarction" href="/articles/myocardial-infarction">myocardial infarction</a>
  • +</li>
  • +<li>acute cor pulmonale</li>
  • +<li>decompensated chronic <a title="Pulmonary hypertension" href="/articles/pulmonary-hypertension-1">pulmonary hypertension</a><ul><li>most commonly due to left sided heart disease</li></ul>
  • +</li>
  • +</ul>

Tags changed:

  • echo
  • pocus
Images Changes:

Image 1 Ultrasound (Subcostal 4 chamber) ( create )

Image 2 CT (C+ arterial phase) ( create )

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