Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Luong D, Feger J, Ventilator induced lung injury. Reference article, Radiopaedia.org (Accessed on 24 Apr 2024) https://doi.org/10.53347/rID-91308
Ventilator-induced lung injury (VILI) is a type of acute lung injury usually inflicted or aggravated by mechanical ventilation. It may occur during invasive or non-invasive ventilation.
Pathology
The predominant mechanisms include:
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alveolar overdistention (volutrauma) / regional lung overdistension
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barotrauma:
- lung injury caused by high transpulmonary pressures
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atelectotrauma:
- lung injury caused by high shear forces from cyclic opening and
collapse of atelectatic but recruitable lung units.
- inflammation
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1. Carrasco Loza R, Villamizar Rodríguez G, Medel Fernández N. Ventilator-Induced Lung Injury (VILI) in Acute Respiratory Distress Syndrome (ARDS): Volutrauma and Molecular Effects. (2015) The open respiratory medicine journal. 9: 112-9. doi:10.2174/1874306401509010112 - Pubmed
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2. J‐D. Ricard, D. Dreyfuss, G. Saumon. Ventilator-induced lung injury. (2003) European Respiratory Journal. 22 (42 suppl): 2s. doi:10.1183/09031936.03.00420103 - Pubmed
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3. Cruz FF, Ball L, Rocco PRM, Pelosi P. Ventilator-induced lung injury during controlled ventilation in patients with acute respiratory distress syndrome: less is probably better. (2018) Expert review of respiratory medicine. 12 (5): 403-414. doi:10.1080/17476348.2018.1457954 - Pubmed
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4. Slutsky, Arthur S., Ranieri, V. Marco. Ventilator-Induced Lung Injury. (2013) doi:10.1056/nejmra1208707
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