Frog eye sign

Changed by Bálint Botz, 26 Apr 2022

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The frog eye sign is seen when the orbital structures show a characteristic protrusion due to fetal anencephaly. The term is particularly used in point of care ultrasound (POCUS) 1

Radiographic features

On obstetric ultrasound the frog eye sign is best appreciated in the coronal plane (in relation to the fetal head). The protruding orbital structures is due to the absence of the fetal calvarium and cerebral tissues cephalad to the orbits. This sonographic appearance is best seen from the second trimester 1,2.  

  • -<p>The <strong>frog eye sign</strong> is seen when the orbital structures show a characteristic protrusion due to fetal <a title="Anencephaly" href="/articles/anencephaly">anencephaly</a>. The term is particularly used in point of care ultrasound (POCUS) <sup>1</sup>. </p><h4>Radiographic features</h4><p>On obstetric ultrasound the frog eye sign is best appreciated in the coronal plane (in relation to the fetal head). The protruding orbital structures is due to the absence of the fetal calvarium and cerebral tissues cephalad to the orbits. This sonographic appearance is best seen from the second trimester <sup>1,2</sup>.  </p>
  • +<p>The <strong>frog eye sign</strong> is seen when the orbital structures show a characteristic protrusion due to fetal <a href="/articles/anencephaly">anencephaly</a>. The term is particularly used in point of care ultrasound (POCUS) <sup>1</sup>. </p><h4>Radiographic features</h4><p>On obstetric ultrasound the frog eye sign is best appreciated in the coronal plane (in relation to the fetal head). The protruding orbital structures is due to the absence of the fetal calvarium and cerebral tissues cephalad to the orbits. This sonographic appearance is best seen from the second trimester <sup>1,2</sup>.  </p>

References changed:

  • 1. Hall J, Denne N, Minardi J, Williams D, Balcik B. Check the Head: Emergency Ultrasound Diagnosis of Fetal Anencephaly. West J Emerg Med. 2016;17(4):460-3. <a href="https://doi.org/10.5811/westjem.2016.5.30326">doi:10.5811/westjem.2016.5.30326</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/27429697">Pubmed</a>
  • 2. Chatzipapas I, Whitlow B, Economides D. The 'Mickey Mouse' Sign and the Diagnosis of Anencephaly in Early Pregnancy. Ultrasound Obstet Gynecol. 1999;13(3):196-9. <a href="https://doi.org/10.1046/j.1469-0705.1999.13030196.x">doi:10.1046/j.1469-0705.1999.13030196.x</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/10204212">Pubmed</a>

Sections changed:

  • Signs

Systems changed:

  • Obstetrics
Images Changes:

Image 1 Ultrasound (Coronal) ( create )

Image 2 Ultrasound (Oblique) ( create )

Image 3 Ultrasound (Coronal view of fetal face) ( create )

Image 4 Ultrasound ( create )

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