Achondrogenesis 1A

Achondrogenesis type Ia, also known as the Houston-Harris subtype, is a subtype of achondrogenesis. It is an extremely rare lethal skeletal dysplasia (chondrodysplasia) with a characteristic severe disarrangement of endochondral ossification.

Some of the common clinical features include:

The growth plate cartilage completely lacks columnar-zone formation and shows chondrocyte expansion due to intracellular vacuoles. 

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Article information

rID: 22076
Tag: cases
Synonyms or Alternate Spellings:
  • Houston-Harris sub type
  • Houston Harris achondrogenesis
  • Achondrogenesis type 1a
  • Achondrogenesis type Ia
  • Type 1a achondrogenesis
  • Houston-Harris sub type - achondrogenesis 1A

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