Achondroplasia (mnemonic)
Updates to Article Attributes
A mnemonic to remember the common features of achondroplasiais:
ACHONDROPLaSIA F
Mnemonic
A: autosomal dominant inheritance, alteration (mutation) of FGFR3
H: hand abnormalities (trident hand, brachydactyly)
O: out knees, bOwing of legs (genu varum)
N: narrowing of interpedicular distance, narrowed foramen magnum, neurological complications, nasal bridge (depressed/narrowed)
D: decreased acetabular angle, delayed motor milestones
R: rhizomelic (short limbs)
O: obesity
P: posterior vertebral body scalloping, proximal limb shortening
La: large head (frontal bossing)
S: squared iliac wings (tombstone configuration), short stature
I: impaired endochondral ossification
A: anterior flaring of the ribs (metaphyseal flaring), anterior beaking of the vertebral body (bullet-shaped vertebra)
F: fibroblast growth factor gene 3
(FGFR3(FGFR3) mutation, frontal bossing, flattened nasal bridge
-<li><p><strong>A: </strong>autosomal dominant inheritance, alteration (mutation) of FGFR3</p></li>- +<li><p><strong>A: </strong>autosomal dominant inheritance, alteration (mutation) of <em>FGFR3</em></p></li>
-<li><p><strong>F: </strong>fibroblast growth factor gene 3 (FGFR3) mutation, frontal bossing, flattened nasal bridge</p></li>- +<li><p><strong>F: </strong>fibroblast growth factor gene 3 (<em>FGFR3</em>) mutation, frontal bossing, flattened nasal bridge</p></li>
Sections changed:
- Mnemonics
Systems changed:
- Musculoskeletal
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