Citation, DOI, disclosures and article data
Citation:
Iqbal S, Yap J, Baba Y, et al. Acinar cell carcinoma of the pancreas. Reference article, Radiopaedia.org (Accessed on 28 May 2023) https://doi.org/10.53347/rID-87933
Pancreatic acinar cell carcinoma is a rare exocrine neoplasm that comprises ~1% of all pancreatic tumors. This tumor shows more aggressive behavior than the far more common adenocarcinoma 1,3,4.
High levels of serum lipase, due to hypersecretion syndrome, resulting in subcutaneous fat necrosis form part of its presentation 2,3,5.
CT
on contrast-enhanced CT, generally presents as an enhancing, ovoid, solid pancreatic tumor
variable hypo/hyperattenuating mass relative to the pancreas, with well-distinguished margins
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non-biliary duct dilation
hypovascular tumor with adjacent organ invasion
internal calcification (50% of cases)
tumor encapsulation
peripancreatic lymph nodes
Treatment and prognosis
In cases of disease confinement to the pancreas, surgical resection is curative and in cases of distant metastasis, surgery followed by chemotherapy and radiotherapy is the treatment of choice 1,2,4.
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