Acinic cell carcinoma (lung)

Acinic cell carcinoma of the lung (also known as a Fechner tumour) is a type of lung carcinoma of the salivary gland type. It is extremely rare, especially when it presents in the form of primary acinic cell carcinoma.

Histologically, they are comprised of clear cells with abundant granular cytoplasm growing as solid sheets with focal acinar, microcystic, and papillocystic regions. Immunohistochemical stains tend to show strong positivity for:

  • low-molecular-weight cytokeratins
  • epithelial membrane antigen (EMA)

Can be variable, encompassing 1:

  • subpleural nodules in proximity to secondary bronchi
  • endobronchial tumours leading obstructive symptoms
  • well-circumscribed deep parenchymal nodules

Acinic cell carcinoma of the lung tends to have a more indolent behaviour and favourable prognosis than other types of lung cancer.

Lung cancer
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Article information

rID: 36525
System: Chest, Oncology
Tag: cases
Synonyms or Alternate Spellings:
  • Acinic cell carcinoma of the lungs
  • Lung carcinoma - acinic cell type
  • Fechner tumours
  • Fechner tumour
  • Fechner tumor
  • Fechner tumors
  • Primary acinic cell carcinoma of the lung

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