Last revised by Arlene Campos on 23 Feb 2024

Acrocephalosyndactyly syndromes (ACS) are a rare group of disorders collectively characterized by:


While there can be some overlap in features, they can be primarily classified into the following major subtypes:

When there are calvarial anomalies with polydactyly and syndactyly, these then fall into a group named acrocephalopolysyndactyly syndromes (ACPS). However, many suggest that the distinction between ACS and ACPS should be abandoned ref.

ADVERTISEMENT: Supporters see fewer/no ads

Cases and figures

  • Case 1: Apert syndrome
    Drag here to reorder.
  • Updating… Please wait.

     Unable to process the form. Check for errors and try again.

     Thank you for updating your details.